Infectious Diseases Flashcards

1
Q

Describe the symptoms and vaginal discharge in bacterial vaginosis (Gardnerella)?

A

white or grey; fishy odor; non-pruritic, no vaginal erythema; pH above 4.5

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2
Q

Describe the symptoms and vaginal discharge of trichomonas infection.

A

yellow-green and pruritic; may have “strawberry cervix”; malodorous; pH above 4.5

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3
Q

Describe the symptoms/vaginal discharge of vaginal candidiasis.

A

odorless, cottage cheese-like discharge w/ significant irritation and inflammation

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4
Q

What vaginal infection shows clue cells on Pap smear?

A

gardnerella

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5
Q

What is the treatment for vaginal candidiasis?

A

vaginal clotrimazole or oral fluconazole

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6
Q

What is the treatment for bacterial vaginosis?

A

metronidazole or clindamycin; oral or vag

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7
Q

In 25% of cases, drug fever is accompanied by _______ and _______.

A

eosinophilia and rash

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8
Q

What Dx can be made w/ 2 or more of the following in the absence of an unknown cause: temp >38.0 or 90; RR > 20 or Pco2 12,000 or 10% band forms?

A

SIRS

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9
Q

How do you define sepsis?

A

SIRS in response to a confirmed infectious process

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10
Q

How do you define severe sepsis?

A

Sepsis w/ evidence of end-organ damage

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11
Q

How do you define septic shock?

A

Sepsis-induced hypotension or hypoperfusion abnormalities despite adequate fluid resuscitation.

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12
Q

What anti-influenza agent is most appropriate for an asthmatic pt?

A

oseltamivir

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13
Q

What kind of anit-influenza drugs are oseltamivir and zanamivir?

A

neuraminidase inhibitors

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14
Q

Name one of the preferred initial treatments for acute bacterial rhinosinusitis.

A

3-10 days of a narrow-spectrum antiobiotic: amoxicillin, TMP-SMX, or doxycycline

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15
Q

What is the preferred empiric treatment for pyelonephritis in a compliant pt w/ no nausea and vomiting? (drug and duration)

A

oral levofloxacine - 7-14 days

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16
Q

What is the preferred empiric treatment for uncomplicated UTI? (drug and duration)

A

TMP-SMX - 3 days

17
Q

In what cases of UTI would you choose to use amoxicillin (7 days)?

A

culture-proven Enterococcus infection - esp. in pregnancy, when TMP-SMX and fluoroquinolones are contraindicated

18
Q

What drug, other than amoxicillin, may be used to treat UTI in a pregnant woman?

A

1st gen cephalosporin, such as cephalexine

19
Q

What is the most appropriate Tx for uncomplicated genitasl herpes outbreak?

A

oral valacyclovir

20
Q

In a pt w/ a skin rash, what is potassium hydroxide stain of skin scrapings meant to look for?

A

tinea corporis or any fungus

21
Q

What is the only significant disease that occurs in AIDS w/ a CD4 ct below 200, but above 100?

A

Pneumocystis jiroveci

22
Q

What is the first diagnostic step for an AIDS pt w/ dysphagia and odynophagia?

A

administration of fluconazole

23
Q

What is the most common cause of dysphagia and odynophagia in HIV pts w/ low T-cell cts?

A

Candida

24
Q

AIDS pt w/ dysphagia and odynophagia: fluconazole doesn’t work. What is the next step?

A

upper endoscopy

25
Q

At what CD4 count does Kaposi’s sarcoma begin to occur?

A

Trick question! No CD4 depression necessary!

26
Q

What are the cutoffs of PPD induration for the various risk-categories?

A

<5 - immunocompromised

27
Q

What is the recommended treatment for latent TB?

A

Isoniazid for 9 mos.

28
Q

What is the antibiotic of choice for bacterial aspiration pneumonia?

A

clindamycin

29
Q

What are the 2 options for treating a pt w/ in the internal medicine ward with CAP?

A

1) beta-lactam + macrolide or doxycycline
or
2) fluoroquinolone monotherapy

30
Q

What is the empiric therapy for a pt w/ CAP in the ICU?

A

beta-lactam + macrolide or fluoroquinolone

31
Q

What are the options for treating CAP in the outpatient?

A
advanced generation macrolide (e.g. azithromycin or clindamycin) OR
a ketolide (telithromycin) OR
doxycycline