Introduction to Inflammation Flashcards Preview

Hugh's MD2 Gen Med > Introduction to Inflammation > Flashcards

Flashcards in Introduction to Inflammation Deck (15):
1

What are some causes of erythema nodosum?

Viral illness

Drug reaction

OCP

2

How does stenosis differ in giant cell arteritis cf to artherosclerosis?

GCA is a more smooth, tapered stenosis

3

What are some negative acute phase reactants?

Albumin

Hb (more chronic)

3

What are the target tissues and antigens in ANCA?

Kidney's

Lungs

Sinuses

 

Cytoplasmic component of neutrophils

4

What are the two commonest way coeliac's presents (non-symptoms)?

Fe deficient anaemia

Hypoalbuminea secondary to malabsorption

4

What rash is rarely present in coeliac's?

Dermatitis herpatiformis

4

What is the commonest vasculitis?

Giant cell arteritis

5

What is distinct about malar rashes?

Sparing of the nasolabial fold

7

What are the target tissues and antigens in Grave's disease?

Thyroid

 

TSH receptor, TPO, thyroglobulin

8

To what targets are antibodies produced against in lupus?

Ro (SSA) and La (SSB) - ribonucleoproteins

dsDNA

snRNP core protein

Thrombin

Histones

9

What is giant cell arteritis aka?

Temporal cell arteritis

11

What is the target tissues and antigen in RA?

Synovial membrane

IgM Fc

13

What are the target tissues and antigens in Goodpasture's?

Kidney, lungs

 

Type 4 Collagen (basement membrane)

14

What is the biggest risk factor for the development of autoimmune disease?

Advancing age

15

Does vasculitis preferentially effect arteries or veins generally?

Arteries