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Hugh's MD2 Gen Med > Professor Russell Tutorial > Flashcards

Flashcards in Professor Russell Tutorial Deck (12):
1

What is a clinical sign of hepatoma?

Occasionally a systolic arterial bruit is heard over the liver as the hepatoma is highly vascular

2

What finding on Fe studies is diagnostics for haemochromatosis?

A transferrin saturation of >65%

3

What is the diagnostic test for hepatocellular carcinoma?

Serum alpha-fetoprotein may be raised (but is normal within 1/3 of patients)

4

What are the mainstays of treatment for hepatocellular carcinoma?

Surgical resection if possible

Liver transplantation

Chemoembolisation or embolisation alone

5

What is diaphoresis?

Perspiration or profuse sweating

6

What are the signs of acute hepatitis?

Metabolic flap (asterixis)

Foetor hepaticus

Jaundice

Disorientation, drowsiness

Ascites

Right hypochrondrium pain

7

What is Budd-Chiari syndrome? What are some causes of Budd-Chiari syndrome?

Obstruction of the venous outflow of the liver due to occlusion of the hepatic vein. 

1/3 of cases unknown cause, other causes include: hypercoagulability states; polycythaemia vera, OCP, leukaemia

 

8

When does leukonychia occur (biochemistry wise)

Serum albumin <25g/L

9

What clotting factors are produced by the liver?

Factors II, VII, IX and X

10

What is Wilson's disease?

A rare inborn error of copper metabolism that results in copper deposition in various organs (liver, basal ganglia and cornea)

Defect in copper-transporting ATPase

11

What are the six extragastrointestinal sites of IBD manifestation?

Eyes

Skin

Joints - axial or peripheral

Liver

Brain

Kidneys

12

What are some the 10 causes of colitis?

Crohn's 

UC

NSAIDs

Infection - C. diff, Shigella, Salmonella, campylobacter, Entamoeba histolytica, giarrdia, cryptosporidium, CMV

Radiotherapy

Collagenous colitis

OCP

Vasculitis

CAPs

Ischaemic