Flashcards in L55 Deck (23)
What bug causes syphilis?
What are the 4 stages of disease for treponema pallidum?
Symptoms of 1ary syphilis
Chancre = painless ulcer on genitals
Symptoms of 2ary syphilis
Swollen lymph nodes
Spotted rash all over body (including palms & soles)
Symptoms of late syphilis
Chronic inflam + granulomatous lesions
CNS involvement = neurosyphilis
BV involvement = cardiovascular syphilis
How do you diagnose syphilis?
1st = RPR/VDRL
Follow up if + = FTA-ABS
What kind of serology test are RPR, VDRL? What info do these diagnostics give you?
Non-treponemal aka non-specific tests
Used to rule out syphilis - high FPs
What kind of serology test is FTA-ABS?
Treponemal = specific tests
Could use doxy
What bug causes Lyme disease
How would you stain for borrelia?
Giema stain (silver)
Ixodes ticks on deer or mice
Transmission requires prolonged feeding (24 hrs)
3 stages of Lyme disease
Symptoms of early, localized Lyme
Symptoms of early, disseminated Lyme
Timeframe = 3-5 wks post bite
1. CN7 palsy (has forehead involvement) - 1 sided facial palsy
3. Cardiac dysfxn (reversible, heart block)
Symptoms of late, disseminated Lyme
Diagnose borrelia burgdorferi
If see erythema migrans - that's enough!
Otherwise ELISA confirmed w/ Western blot
Treat Lyme - 1st & 2nd choices
2nd choice = ceftriaxone
Which bug is transmitted in contaminated water via skin cuts?
Chronically infects kidneys of animals - pee bug into waters
What are symptoms of Leptospirosis?
1. Septicemic - acute, eye symptoms
2. Immune - 1 mo after, liver + kidney failure
Penicillin or doxy