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Flashcards in L59 Deck (23):
1

What are the 3 organisms most likely to cause dermatophyte infection?

1. Microsporum - WON'T cause tinea unguium
- More common worldwide cause
2. Epidermophyton - common cause of tinea cruris
3. Trichophyton - most common US cause

2

What diseases are caused by dermaphytes?

Tinea + body part

3

What are the 2 types of tinea capitis?

Ectothrix - outside --> in destruction
- Does not damage hair bulb, hair will likely grow back
Endothrix - infection starts inside the hair bulb --> out

4

Which bug usually causes endothrix tinea capitis?

T.tonsurans = US
Microsporum world wide

5

What patients usually get tinea capitis?

Kids!

6

Treat tinea capitis

1. Shampoo
2. PO terbinafine
3. Wash everything that could be contaminated!

7

What are the 3 types of tinea pedis?

Interdigital
Moccasin
Vesiculobullous

8

How do you get tinea corporis?

Direct body contact
- To humans: wrestlers
- To animals: horses

9

What is a tinea infection of the nails called?

Onychomycosis

10

How do you get/treat onychomycosis?

Can get independently or as a progression of other tinea infections (tinea pedis)
Treat with PO always! Need to penetrate the nail
- Terbinafine

11

If you're using terbinafine as your first choice anti-fungal in most cases when you need a PO drug, what is your second choice?

Itraconazole

12

How do you treat most tineas (skin based infections)?

Topical: clotrimazole + miconazole
Add PO if severe

13

What bug causes tinea versicolor?

Malassezia furfur

14

What are the symptoms of tinea versicolor?

Hyper/hypopigmentation
Dandruff
Dermatitis
Folliculitis

15

If you scrape sample tinea versicolor, what do you see?

Spaghetti and meatballs

16

Treat tinea versicolor.

Shampoo + scrubbing
2. Terbinafine

17

Dermophytes cause cutaneous mycoses. What is unique about this level of infection?

Will see inflammation b/c invading dermis - interacting with immune cells

18

What do microsporum look like under the microscope?

Bottle nose!

19

What are the 3 types of reservoirs for dematophyte infections?

Anthropophilic - humans
- Use us for our keratin!
- We fight off with cellular immunity
Zoophilic - animals
Geophilic - soil

20

Type of trichophyton that is most common cause of tinea pedis

T.rubrum

21

Symptoms of tinea capitis

Papules
Nodules
Inflam = scaling, alopecia

22

Define kerion

In tinea capitis - endothrix (T.tonsurans)
Result of cell mediated immune response
Severe inflam, hair loss, cervical lymphadenopathy

23

How can you diagnose a dermatophyte?

KOH prep
Calcofluor prep