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LATG > LATG Final Review > Flashcards

LATG Final Review Flashcards

1
Q

What is a major advantage of fluoroscopy over standard radiography?

A

it takes moving pictures

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2
Q

Continuous exposure to acoustical levels above what level can have both auditory and non-auditory effects?

A

85 db

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3
Q

What method is used to diagnose coccidiosis in rabbits?

A

fecal float

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4
Q

What is a serious complication associated with the use of the anesthetic tribromoethanol?

A

intestinal ileus

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5
Q

What cell type is a component of the innate immune system?

A

Phagocytes

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6
Q

What purpose do subsidies serve?

A

To reduce costs to run the facility

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7
Q

What is the term used to describe an animal with a normal immune system?

A

immunocompetent

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8
Q

Which type of radiation is electromagnetic radiation generated from radioactive decay?

A

gamma radiation

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9
Q

Thick dense shielding must be used to protect a worker from what type of radiation?

A

gamma radiation and x-rays

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10
Q

What is the product of replication?

A

DNA

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11
Q

Who usually establishes the majority of the unit’s goals?

A

upper-level management

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12
Q

Along with the development and coordination of emergency plans with local community response groups, what else do community right-to-know ordinances require?

A

A list of hazardous chemicals and their location

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13
Q

What is an appropriate starting point for preparing a budget of expenses for the next fiscal year?

A

the amount of money spent in the previous fiscal year

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14
Q

Which agency administers the Animal Welfare Act?

A

APHIS

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15
Q

What should be used to clear Clostridium pilliforme from equipment?

A

An antisporicidal sterilant

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16
Q

Heavy equipment, sharps, and animal bites are considered what type of hazard?

A

physical

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17
Q

Which zoonotic viral disease often remains asymptomatic in infected macaques and can be fatal in humans?

A

B virus

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18
Q

Which imaging technique uses a radioisotope to provide images of in vivo biological processes?

A

Positron emission tomography

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19
Q

What document states that an animal facility must develop a disaster plan?

A

The Guide

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20
Q

What best describes a congenic strain?

A

The result of backcrossing for 10 generations

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21
Q

What is the term for a molecule that is composed of a series of chemical subunits which are linked together?

A

polymer

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22
Q

What group of worms are generally elongate, cylindrical, and non-segmented?

A

nematodes

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23
Q

_______ allows lipids to be absorbed through the wall of the small intestine and used as energy in the body.

A

bile

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24
Q

Hemoglobin is the:

A

oxygen carrying component of RBCs

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25
Q

To reduce the chance of contracting orf, what precaution should always be taken by personnel handling sheep?

A

wear gloves

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26
Q

What ABSL level should be used when working with an agent whose risk of transmission is unknown?

A

4

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27
Q

What do the “N,” “R,” and “P” in the description of respirators refer to?

A

The respirator’s filter resistance to oil in aerosol

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28
Q

Animals that have a normal intestinal flora but are free of particular organisms are called:

A

specific pathogen free

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29
Q

If a transgene is integrated in one of the chromosomes of a pair, the animal is said to be:

A

hemizygous

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30
Q

The roles of cell-to-cell communication and self-recognition by the immune system are fulfilled by:

A

glycoproteins

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31
Q

A bacterial septicemia that occurs frequently in frogs and that can cause erosion of the toes, feet, and jaws is called:

A

red leg

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32
Q

What does an ultrasonic Doppler flow detector measure?

A

blood pressure

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33
Q

What differentiates proficient performance of a task with competent performance of the task?

A

consistent accuracy and efficiency

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34
Q

Statistical analysis is used to:

A

draw conclusions based on the data from a study.

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35
Q

What is the tell-tale sign of a pregnant mouse?

A

budging abdomen

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36
Q

Mycobacteriosis in fish is thought to spread through what?

A

cannibalism of tank mates

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37
Q

What is the concern when disposing of bedding from healthy animals?

A

allergenic aerosols

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38
Q

What biomolecule carries the cell’s genetic information across the nuclear membrane?

A

mRNA

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39
Q

What type of radiation is electromagnetic radiation generated non-radioactively?

A

X-rays

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40
Q

In protein synthesis, during which step is messenger RNA formed?

A

transcription of DNA

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41
Q

A white blood cell differential is also known as a:

A

leukogram

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42
Q

If a genetically modified mouse is dying and cannot be saved, it is important to attempt to save which of the following?

A

gonads

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43
Q

How does the IACUC address the animal and physical plant chapters of the semiannual Program and Facility Review Report it must file with OLAW?

A

semi-annual investigation

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44
Q

Which organelle uses information contained in the mRNA to connect amino acids and form a protein?

A

Ribosome

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45
Q

Organic acids consisting of a chain of hydrocarbons are __________.

A

fatty acids

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46
Q

What is the primary sign of orf?

A

blisters

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47
Q

What disease is characterized by fish rubbing their sides and flipping around in the corners of the tank?

A

velvet disease

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48
Q

Using Western blot, what enables visualization of the protein?

A

antibodies

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49
Q

For which purpose does the transfer sleeve of an isolator have nipples?

A

sterilant injection

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50
Q

What is blended learning?

A

learning from 2 or more training modalities

51
Q

In rebreathing systems, the exhaled gases pass through a canister that absorbs what?

A

carbon dioxide

52
Q

What describes carbon-14 (14C), tritium (3H), and Iodine-125 (125I)?

A

radioisotopes

53
Q

A verification of what has been learned is the definition of which term?

A

assessment

54
Q

Which USDA publication clarifies the intent of the Animal Welfare Act?

A

Animal Care Policy Manual

55
Q

What term is used for the quantity of the drug per unit of body weight?

A

dose rate

56
Q

What is the product of translation?

A

Protein

57
Q

________ helps to eliminate personal bias from a study and to allow the independent variable to control.

A

Randomization

58
Q

What is the stage when a protozoan parasite actively multiplies?

A

Trophozoite

59
Q

What is the causative agent of Tyzzer’s disease?

A

Clostridium piliforme

60
Q

Otitis externa in cats may be associated with infestation by what arthropod?

A

Notoedres cati

61
Q

In which phase of the ADDIE instructional design model does the needs assessment take place?

A

analyze

62
Q

What is the term for the solid media used to grow bacteria?

A

agar

63
Q

If you are anesthetizing a 5 kg dog using a rebreathing system, what capacity would you choose for the rebreathing bag?

A

600ml

64
Q

Toxocara canis is which type of parasite?

A

ascarid

65
Q

In which group of helminths are tapeworms found?

A

cestodes

66
Q

What disease causes lethargy and excessive mucus and white spots on the skin of fish?

A

ich

67
Q

An imbalance in the different types of lipoproteins (HDL versus LDL) is a major contributing factor in what disease?

A

Atherosclerosis

68
Q

What method of reporting an incident is most likely to lessen consequences from funding or regulatory agencies?

A

self-report

69
Q

Technology using adenosine triphosphate (ATP) test swabs uses _______ to measure organic residue.

A

light

70
Q

When a report of noncompliance is deemed by OLAW to be a violation of the Animal Welfare Act, who does OLAW inform?

A

USDA

71
Q

What symptoms are characteristic of microsporidiosis in fish?

A

Emaciation and spinal curvature

72
Q

The first step in developing a disaster plan should be to:

A

identify the types of disasters which might affect the facility.

73
Q

What is the overall goal of a good security plan?

A

To minimize damage and quickly restore a safe and fully functioning environment.

74
Q

When wild type females are bred to hemizygous males, what percentage of the resulting pups can be expected to have the transgene?

A

50%

75
Q

Radioactive isotopes can be attached to which molecule in positron emission tomograph?

A

glucose

76
Q

What is used to represent an estimate of the reasonable level of a chemical to which a worker can be exposed without adverse effects?

A

threshold limit value

77
Q

At which level of Maslow’s hierarchy of needs would you place providing adequate security in the facility?

A

safety needs

78
Q

What disease in fish can be successfully treated with repeated dilute formalin baths?

A

Ich

79
Q

What is recommended for animals such as genetically engineered rodents obtained from sources other than licensed vendors?

A

Quarantine upon arrival

80
Q

What must be the basis of any increase in rates?

A

cost analysis

81
Q

In which room access type are primary investigators allowed to conduct some manipulations, although facility personnel have the majority of contact with the animals?

A

limited access

82
Q

What management function most directly affects accomplishment of the mission of the institution and animal care program?

A

goal setting

83
Q

What component of the innate immune system coats the surface of invading organisms to facilitate their attack by the macrophages?

A

complement proteins

84
Q

Cannibalism of new pups is a frequent problem in which mouse strain?

A

C57BL/6

85
Q

How would you classify the athymic mouse’s immunodeficiency?

A

a primary immunodeficiency disease

86
Q

In what species does the administration of morphine frequently induce vomiting and defecation?

A

dogs

87
Q

Ringworm is an example of what?

A

Cutaneous mycosis

88
Q

What do high concentrations of neutrophils usually indicate?

A

active bacterial infection

89
Q

How often should a research facility using regulated species update their USDA registration?

A

every 3 years

90
Q

Blood types are characterized by the carbohydrate portions of _______ on the surface of cells and the carbohydrate portion of serum _______.

A

glycolipids, glycoproteins

91
Q

What term refers to the thousands of microbial species that inhabit a specific host?

A

microbiome

92
Q

Providing each staff member with specific training regarding GLPs is whose responsibility at the institution?

A

QA unit

93
Q

If swine are unable to access water, they may develop:

A

salt toxicity

94
Q

A good way to screen the health status of incoming animals is to:

A

request several extra animals from the vendor to use for health screening.

95
Q

What best describes genetic engineering?

A

Manipulating DNA molecules to alter their composition

96
Q

Using the pronuclear injection technique, what is the average percentage of offspring carrying the transgene?

A

20%

97
Q

A nonrebreathing system is used for animals of what weight range?

A

less than 5kg

98
Q

What is typical of a secondary (anamnestic) immune response?

A

The serum titer rises to a higher level than during the primary response.

99
Q

Guinea pigs housed on wire floors may have inflamed, swollen, and painful feet due to infection with what organism?

A

Staphylococcus aureus

100
Q

Carbohydrates made up of two monosaccharides are classified as:

A

Disaccharides

101
Q

Which carbohydrate is the primary source of energy used for metabolic processes?

A

glucose

102
Q

What are hydatid cysts?

A

Fluid-filled cyst containing tapeworm larvae

103
Q

What breaks down dietary fiber?

A

bacteria

104
Q

What represents a difference between the Animal Welfare Act and the PHS Policy?

A

PHS Policy covers mice, rats, and birds.

105
Q

What does a pulse oximeter measure?

A

level of oxygen in blood

106
Q

Heating devices used to maintain the body temperature of anesthetized animals should be ___________ the animal’s normal body temperature.

A

1-2 degrees higher than

107
Q

Bacteria that can grow in the absence of oxygen are known by what term?

A

anaerobic

108
Q

What are the three steps involved in an acquired immunity response to a foreign substance?

A

Recognition, amplification, and resolution

109
Q

What best defines the term “variable” as used in the biomedical research field?

A

It represents anything that can affect the results of a study.

110
Q

What tissue type is used to test for mouse parvovirus?

A

lymph node

111
Q

Under which condition will viruses grow?

A

cell culture

112
Q

What is the tidal volume for most laboratory animals?

A

15-20ml/kg

113
Q

A mycelium is formed by what?

A

A mold colony

114
Q

What antibiotics are preferred to treat enteric coccidiosis?

A

Sulfonamides

115
Q

What information is gained from continuous monitoring of blood pressure?

A

cardiac output

116
Q

Post-anesthetic behavioral changes can persist for up to ___ hours in animals administered dissociative anesthetics.

A

24

117
Q

What carbohydrate serves as energy storage in animals?

A

glycogen

118
Q

Helicobacter spp. are most commonly diagnosed with what technique?

A

PCR

119
Q

What is one precaution that must be considered when using urethane as an anesthetic agent?

A

It must be used with protective equipment.

120
Q

For what condition are cephalosporins often used?

A

Conditions that have shown resistance to other antibiotics

121
Q

To prevent ruminants from suffering positional bloat during a surgical procedure, what measure is typically taken during the procedure?

A

placement of rumen tube

122
Q

Cats are the definitive host of which species of apicomplexan parasite?

A

Toxoplasma gondi

123
Q

What is the most important component of the Hazard Communication Standard (HCS) right-to-know program?

A

employee training

LATG (24 decks)

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