LEC 5 Flashcards

1
Q

def? decreased O2 carrying capacity of blood, due to either insufficient Hb or abnormally functioning Hb

A

anemia

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2
Q

what are the symptoms of anemia

A

fatigue and shortness of breath

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3
Q

what kind of anemia has pts that crave unusual substances

A

IDA

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4
Q

if anemia is asymptomatic what does that tell you

A

slow progression

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5
Q

what will be on the skin of people with anemia

A

petechiae

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6
Q

what will pts with anemia eyes look like (3)

A

pallor, jaundice, or hemorrhage

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7
Q

what will pts with anemia mouth look like

A

mucosal bleeding

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8
Q

what will pts with anemia heart do

A

have cardiac murmurs or arrhythmias

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9
Q

t or f: people with anemia will have sternal tenderness

A

t

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10
Q

describe someone with asymptomatic anemia heart beat

A

normal

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11
Q

what happens in ineffective erthropoiesis

A
  • erythroid precursors are defective
  • most cells die the BM
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12
Q

what is the issue with megaloblastic anemia, thalassemia, sideroblastic anemia

A

ineffective erythropoiesis

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13
Q

what happens in insufficient erythropoiesis

A

number of erythroid precursors produced in BM is low

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14
Q

what will increase in a pt treated with anemia in 7-10 days

A

reticulocytes

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15
Q

what does MCHC tell you about anemia

A

type

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16
Q

what does RDW tell you about anemia

A

if retics are present

17
Q

if someone has anemia what is found in a urine test

18
Q

_____ is often a symptom of another disease

19
Q

what kind of cell size? MCV < 80 fL

A

microcytic

20
Q

what kind of cell size? MCV > 100 fL

A

macrocytic

21
Q

what kind of cell size? MCV 80 - 100 fL

A

normocytic

22
Q

morphology? hemolytic anemias

A

normocytic/normochromic

23
Q

what type of anemia is the most common microcytic hypochromic

24
Q

morphology of megaloblastic and non-megaloblastic anemia

A

macrocytic/ normochromic

25
what type of anemia has BM failure
aplastic
26
what groups are most at risk for IDA
menstruating women, pregnancy, and breast feeding
27
what disease would have these test ordered: evaluation of heme synthesis, free erythrocyte protoporophyrin, soluble transferrin receptor, and BM evaluation
IDA
28
what is the problem with heme synthesis
abnormality of heme synthesis
29
morphology of sideroblastic anemia
microcytic and hypo chromic
30
def? accumulation of iron in mitochondria around the nucleus
ringed sideroblast
31
what chromosome is linked to sideroblastic anemia
X
32
what disorder will lead to sideroblastic anemia
lead poisoning
33
what accumulates in heme synthesis of sideroblastic anemia pt
ALA, iron, and protoporphyrin
34
what is the diff between pappenheimer bodies and sideritic granules
can not see all sideritic granules in wright stain
35
what kind Hb is increased in beta thalassemia minor
Hb A2
36
IDA stage? - iron stores are depleted - RBCs not effected
stage 1
37
IDA stage? - RBCs are produced with not the proper amount of Hb
stage 2
38
IDA stage? - IDA has developed - symptoms are present
stage 3