Lecture 10: Cartilage Histology Flashcards Preview

04. MSK Exam 2 Final > Lecture 10: Cartilage Histology > Flashcards

Flashcards in Lecture 10: Cartilage Histology Deck (29)
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1

What distinguishes one type of cartilage from another?

The Extracellular Matrix differs between types

2

What structures does cartilage lacks supply from?

Nerves

Blood Vessels

Lymphatics

3

What secretes the cartilage matrix?

Chondroblasts

Has mitotic capabilities 

4

Where do chondrocytes come from?

Chondroblasts

5

What do you call a group of several chondrocytes in close proximity to each other?

An Isogenous Group

6

What is the structure that chondrocytes are housed in?

Lacunae: hollow space in the extracellular matrix of cartilage 

7

What type of fibers is found in the cartilage matrix?

What is the most common

  • Type II Collagen (most predominant)
  • Type I Collagen
  • Elastin Fibers (elastic cartilage) 

8

Where does cartilage arise from?

Embryonic Mesenchyme 

Differentiation takes places from center to outward

9

What is the role of perichondrium?

 

 

  • Essential from growth and maintenance of cartilage
  • Holds the cartilage in place

10

What kind of connective tissue is the perichondrium?

Dense irregular connective tissue

11

What types of cartilages has a perichondrium?

Which types lack it?

Perichondrium Present:

  • Hyaline Cartilage
  • Elastic Cartilage

Perichondrium Absent

  • Hyaline Articular Cartilage
  • Fibrocartilage

12

What are the characteristics of the fibrous (outer) layer of the perichondrium?

Produces Type 1 collagen and fibroblasts

Acts as a transitional zone

13

What are the characteristics of the chondrogenic (inner) layer of the perichondrium?

  • Adjoins cartilage matrix 
  • Contains mesenchymal stem cells that have chondroblasts that can differentiate into chondroblasts
  • Secretes Type II collagen

14

What has a vascular supply, which then allows the cartilage nearby to gain some nutrients?

The perichondrium

15

During periods of cartilage growth, where do new cartilage cells come from?

The perichondrium

16

Hyaline Cartilage

What type of collagen does it use?

Where is it found?

Type II collagen

Found in: Articular Cartilage, Larynx, Trachea, Ribs, Embryonic Developlment

17

What is the hyaline matrix composed of?

Territorial Matrix 

Interterritorial Matrix 

Gives it a glassy, opaque look 

18

What is the epiphyseal plate made of?

Hyaline Cartilage

19

What is the Territorial Matrix?

 

What molecule is it rich in?

What molecule does it have less of?

The more intensely stained portion of cartilage around any given isogenous group.

 

Rich in Glucosaminoglycans [GAGs]

Less Type II Collagen

20

What is the Interterritorial Matrix rich in?

What does it have fewer of?

Type II Collagen

Proteoglycans

Less intense staining 

21

Elastic Cartilage

What type of collagen does it use?

Where is it found?

Type II Collagen and Elastin 

Found in: External Ear, Epiglottis, Auditory tube

22

Fibrocartilage Cartilage

What type of collagen does it use?

Where is it found?

Type I Collagen (Little Type II)

Found in: Intervertebral discs, pubic symphysis, and selected joint capsules

23

What is the purpose of Fibrocartilage?

Withstands compression and shearing forces

24

What is Fibrocartilage made up of in the most basic sense?

Hyaline cartilage and Dense Regular connective tissue

25

What is interstitial growth?

Mitotic division of preexisting chondrocytes in lacunae

Adding volume 

26

What is appositional growth?

Chondroblast differentiation from progenitor cells in perichondrium

 

27

Where do we see type 1 collagen in cartilage?

Fibrocartilage

Outer perichondrium

28

How is repair cartilage different than other types?

 

What kinds of collagen does it contain?

 

What other tissue does it stimulate?

It is an intermediate between Hyaline and Fibrous Cartilage

 

Types 1 and 2

 

Facilitates bone healing - but can cause bone spurs

29

What lines the ends of bones where they meet inside of an articular capsule?

Articular Cartilage

(Hyaline Cartilage with no perichondrium)