Lecture 15

Question 1

What are the two general approaches to diagnose a disease by immunoassays

Answer 1

1. testing for specific antigens

2. Testing for antigen-specific antibodies

Question 2

What is serology most common performed on

Answer 2

Blood samples or the serum or plasma fractions

Question 3

What is an antiserum

Answer 3

Serum collected from an animal that has been exposed to a particular Ag and therefore contains Ab against that Ag

Question 4

What happens when you inject an animal with Ab

Answer 4

The Ab becomes the Ag and you can produce Ab against tine injected Ab

Question 5

What is sensitivity

Answer 5

Probability that a given test will correctly identify animals with the disease

Question 6

What is specificity

Answer 6

Probably that a given test will identify those animals that do not have the disease under consideration

Question 7

What is the positive predictive value of a test

Answer 7

Probability that an animal with a positive test actually has the condition for which the test was conducted

Question 8

Negative predictive value

Answer 8

Probability that an animal with a negative test results is actually free of the condition