Lecture 41 Flashcards Preview

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Flashcards in Lecture 41 Deck (9)
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1
Q

Chylomicrons contain apo____ and are assembled in the _____.

A

They contain apoB48 and are assembled in the INTESTINES.

2
Q

Chylomicrons acquire ____ and ____ from HDL in the plasma.

A

Acquire apoC-II and apoE from HDL

3
Q

apo C-II binds to _____ lipase on the surface of non-hepatic tissues.

A

LIPOPROTEIN lipase

4
Q

Chylomicron remnants, depleted of FFA and Glycerol, return apo ____ to HDL.

A

They return apoC-II to HDL

5
Q

Chylomicron remnants with apo____ and apo____ bind apo____ receptors on hepatocytes, resulting in the uptake of Chylomicron remnants.

A

Remnants with apoE and apoB48 bind apoE receptors on hepatocytes, resulting in the uptake of the remnants.

6
Q

HDL and VLDL are both assembled in the ____, though HDL can be assembled in the intestine as well. VLDL contains apo____

A

LIVER. VLDL contains apoB100

7
Q

VLDL acquires ____ and ____ from HDL, but then returns both, at which point it becomes ____.

A

Acquires apoC-II and apoE from HDL, but then returns both, at which point it becomes LDL.

8
Q

Cholesterol Ester Transfer Protein (CEPT) deficient individuals have increased _____, putting them at lower risk for heart disease.

A

they have increased HDL

9
Q

Familial Hypercholesterolemia is autosomal _____, and arises from a defect (of which there are 4 classes) in the LDL receptor.

A

autosomal DOMINANT