lecture 9 Flashcards

(20 cards)

1
Q

adrenaline

A

hormone, binds all alpha and beta receptors

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2
Q

noradrenaline

A

neurotransmitter, mostly is retaken up, binds mostly alpha receptors

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3
Q

alpha adrenoreceptor

A

everything to do with calming down the body, vasodilation/constriction

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4
Q

beta adrenoreceptor

A

have to do with metabolism, also cardiac arrest and allergies

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5
Q

alpha 2 receptor

A

presynaptic autoreceptor, inhibition of AC, noradrenaline release

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6
Q

isoprenaline

A

binds all beta receptors

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7
Q

alpha 1/2 receptor

A

smooth muscles, glands

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8
Q

beta 1 receptor

A

heart (metabolism)

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9
Q

beta 2 receptor

A

smooth muscles, metabolism, bronchial dilation

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10
Q

beta 3 receptor

A

lipolysis

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11
Q

clonidine, oxymetazoline

A

bind alpha 2 receptor

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12
Q

phenylephrine

A

binds alpha 1 receptor

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13
Q

fenoterol, salbutamol

A

bind beta 2 receptor, short acting inhalation drugs

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14
Q

PLC is activated by which subunits of which proteins

A

beta gamma of Gi and alpha of Gq, causing vasoconstriction

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15
Q

positive chronotrope

A

Na+, increases heart rate, SA node

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16
Q

positive inotrope

A

Ca2+, increases heart contractility, cardiac muscles

17
Q

arrythmia

A

permanent change in heart rate or heartbeat

18
Q

adams stoke attack

A

too much ACh can activate a too active vagus causing fainting

19
Q

renin (kidneys)

A

alpha 2 decreases renin, beta 1 increases renin

20
Q

tyramine

A

helps sodium and NA get into presynaptic area and NA also in vesicles once its there