Lung Cancers Flashcards Preview

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Flashcards in Lung Cancers Deck (23):
1

pneumonic "coin" lesion on X-ray film or noncalcified nodule on CT

Lung Cancer

2

Lung Cancer complications

SPHERE: SVC Syndrome; Pancoast tumor; Horner Syndrome; Endocrine (paraneoplastic); Recurrent Laryngeal Symptoms (hoarseness); Effusions (pleural or pericardial)

3

Central Lung Cancers

Squamous and Small Cell Carcinomas

4

Most common lung cancer in nonsmokers

Adenocarcinoma Lung CA

5

Location of Adenocarcinoma Lung CA

Peripheral

6

Activating mutations associated with Adenocarcinoma Lung CA

k-ras; EGFR and ALK

7

Hypertrophic osteoarthropathy (clubbing)

Adenocarcinoma Lung CA

8

Lung cancer that grows along alceolar septa causing apparent thickening of alveolar walls

Adenocarcinoma Lung CA

9

Keratin pearls and intercellular bridges

Squamous Cell Carcinoma of Lung

10

Cancer that may produce ACTH, ADH, or antibodies against presynaptic calcium channels (Lambert-Eaton)

Small Cell (oat cell) Carcinomar

11

Cavitation, Cigarettes, hyperCalcemia

Squamous Cell Carcinoma of Lung

12

Produces PTHrP

Squamous Cell Carcinoma of Lung

13

Kulchitsky cells

small dark blue cells; associated with Small cell (oat cell) carcinoma

14

Pleomorphic giant cells found in ther Periphery of lung (occasionally central lung)

Large cell carcinoma

15

Chromogranin A (+)

Bronchial carcinoid tumor; it stains Nest of neuroendocrine cells

16

Carcinoid Syndrome

Serotonin secretion; flushing, diarrhea, wheezing

17

Tx of carcinoid Syndrome

Octreotide; somtostatin analog

18

Malignancy of the pleura associated with asbestos

Mesothelioma

19

Result of Mesothelioma

hemorrhagic pleural effusions and pleural thickening

20

Carcinoma that affects the apex of the lung

Pancoast tumor

21

IL ptosis, miosis, and anhidrosis

Horner Syndrome; if Pancoast tumor compresses the cervical sympathetic plexus; SVC syndrome; sensorimotor deficits and hoarseness

22

Pacial Plethora

SVC syndrome, impaired blood drainage from head

23

#1 area lung cancers like to metastasize to

Adrenals