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Flashcards in Mannheimia and Bibersteinia Deck (27)
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1

What differentiates Mannheimia haemolytica and Bibersteinia trehalosi?

Mannheimia haemolytica is trehalose negative, while Bibersteinia trehalosi is trehalose positive

2

________ is the most important bacterial cause of respiratory disease in cattle and sheep

Mannheimia haemolytica

3

______ has also been associated with mastitis in sheep

Mannheimia haemolytica

4

What do the colonies of Mannheimia haemolytica look like?

They are smaller than P. multocida and do not have the same distinct musty odor
Also have a very distinct, thin zone of complete hemolysis

5

T/F All types of Mannheimia haemolytica produce cytotoxins

TRUE; this is also true for Bibersteinia trehalosi

6

The cytotoxin produced by Mannheimia haemolytica is toxic for ________

leukocytes and platelets of ruminants

7

The cytotoxin of Mannheimia haemolytica is considered a ______ toxin

RTX; punches holes in teh cell membrane

8

Low levels of M. haemolytica toxin ______ while high levels lyse the ________ completely

Affect the function of leukocytes
Leukocytes

9

Where is the normal habitat for Mannheimia haemolytica?

Upper respiratory tract of cattle and sheep

10

Transmission of Mannheimia haemolytica?

ingestion or inhalation; Inhalation is the most common

11

What is the form of Mannheimia haemolytica that affects cattle?

Biovar A serotype 1
Serotype 2 is also seen, but it is non-pathogenic

12

_____% of feedlot pneumonia cases are due to Mannheimia haemolytica biovar A serotype 1

90

13

What lesions do you see with Mannheimia haemolytica biovar A serotype 1 infections in cattle?

fibrinous pleuropneumonia that can be involved with shipping fever complex

14

Mannheimia haemolytica can be an important cause of _____ in sheep. It is referred to as blue bag, as it can become gangrenous

mastitis

15

T/F Mannheimia haemolytica is an important organism in swine and horse health as well

FALSE; isolated occasionally but nothing to call home about

16

T/F Killed bacterins provide sufficient immunity against Mannheimia hemolytica

TRUE; they need to be given early and have to be given twice

17

A normal, non-stressed calf is able to withstand low levels of ________

Mannheimia haemolytica

18

______ cells are very important in the lower respiratory tract for defense

Phagocytic

19

High numbers of Mannheimia haemolytica in the lung may allow the organism to ______ and cause severe _______

survive
pneumonia

20

Mannheimia haemolytica _____ is thought to be important in the development of pneumonia

cytotoxin

21

Understand why the leukotoxin of Mannheimia haemolytica can cause pneumonia

Basically it lyses leukocytes, which causes the release of lysosomal enzymes, which causes inflammation in the lung
Inflammed lung tissue is non-functional lung tissue

22

A successful humoral response against Mannheimia haemolytica requires antibody against what two things?

1: the cytotoxin; Can be IgA, IgM, or IgG
2: Cell surface components; efficient killing of the organism

23

______ is an organism that is very similar to Mannheimia haemolytica and produces an identical cytotoxin

Biberstieinia trehalosi

24

Bibersteinia trehalose is associated with ______ in dairy cattle, especially in the _______ portion of the US

severe respiratory disease
Northwest

25

Bibersteinia trehalosi causes _______ in feeder lambs

septicemia

26

Bibersteinia trehalosi enters the body via lesions in the _______

esophagus

27

In some areas of the country, __________ has become the most isolated organism from goats with respiratory disease

Bibersteinia trehalosi