Flashcards in Mannheimia and Bibersteinia Deck (27)
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1
What differentiates Mannheimia haemolytica and Bibersteinia trehalosi?
Mannheimia haemolytica is trehalose negative, while Bibersteinia trehalosi is trehalose positive
2
________ is the most important bacterial cause of respiratory disease in cattle and sheep
Mannheimia haemolytica
3
______ has also been associated with mastitis in sheep
Mannheimia haemolytica
4
What do the colonies of Mannheimia haemolytica look like?
They are smaller than P. multocida and do not have the same distinct musty odor
Also have a very distinct, thin zone of complete hemolysis
5
T/F All types of Mannheimia haemolytica produce cytotoxins
TRUE; this is also true for Bibersteinia trehalosi
6
The cytotoxin produced by Mannheimia haemolytica is toxic for ________
leukocytes and platelets of ruminants
7
The cytotoxin of Mannheimia haemolytica is considered a ______ toxin
RTX; punches holes in teh cell membrane
8
Low levels of M. haemolytica toxin ______ while high levels lyse the ________ completely
Affect the function of leukocytes
Leukocytes
9
Where is the normal habitat for Mannheimia haemolytica?
Upper respiratory tract of cattle and sheep
10
Transmission of Mannheimia haemolytica?
ingestion or inhalation; Inhalation is the most common
11
What is the form of Mannheimia haemolytica that affects cattle?
Biovar A serotype 1
Serotype 2 is also seen, but it is non-pathogenic
12
_____% of feedlot pneumonia cases are due to Mannheimia haemolytica biovar A serotype 1
90
13
What lesions do you see with Mannheimia haemolytica biovar A serotype 1 infections in cattle?
fibrinous pleuropneumonia that can be involved with shipping fever complex
14
Mannheimia haemolytica can be an important cause of _____ in sheep. It is referred to as blue bag, as it can become gangrenous
mastitis
15
T/F Mannheimia haemolytica is an important organism in swine and horse health as well
FALSE; isolated occasionally but nothing to call home about
16
T/F Killed bacterins provide sufficient immunity against Mannheimia hemolytica
TRUE; they need to be given early and have to be given twice
17
A normal, non-stressed calf is able to withstand low levels of ________
Mannheimia haemolytica
18
______ cells are very important in the lower respiratory tract for defense
Phagocytic
19
High numbers of Mannheimia haemolytica in the lung may allow the organism to ______ and cause severe _______
survive
pneumonia
20
Mannheimia haemolytica _____ is thought to be important in the development of pneumonia
cytotoxin
21
Understand why the leukotoxin of Mannheimia haemolytica can cause pneumonia
Basically it lyses leukocytes, which causes the release of lysosomal enzymes, which causes inflammation in the lung
Inflammed lung tissue is non-functional lung tissue
22
A successful humoral response against Mannheimia haemolytica requires antibody against what two things?
1: the cytotoxin; Can be IgA, IgM, or IgG
2: Cell surface components; efficient killing of the organism
23
______ is an organism that is very similar to Mannheimia haemolytica and produces an identical cytotoxin
Biberstieinia trehalosi
24
Bibersteinia trehalose is associated with ______ in dairy cattle, especially in the _______ portion of the US
severe respiratory disease
Northwest
25
Bibersteinia trehalosi causes _______ in feeder lambs
septicemia
26
Bibersteinia trehalosi enters the body via lesions in the _______
esophagus
27
