Francisella, Coxiella, Legionella Flashcards Preview

Micro Exam 3 > Francisella, Coxiella, Legionella > Flashcards

Flashcards in Francisella, Coxiella, Legionella Deck (17)
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1

What is the one species of Francisella we are concerned with?

Francisella tularensis

2

Fracisella is the cause of what?

tularemia or rabbit fever

3

The biovar ______ is found only in North America

tularensis

4

Francisella biovar ________ is distributed more widely and is fevered to as ______ fever as it is associated with this animal

palaearctica
beaver

5

Francisella biovar _____ is a cause of human disease

novicida

6

What are the hosts for biovar tularensis and biovar palaeartica?

tularensis: ticks, wild rodents, and rabbits
palaeartica: beavers

7

What is the only way Francisella is spread to humans?

Via contact with rabbit or beaver/rodent
Via deer fly or tick bite (most common)

8

T/F The infectious dose of Francisella is very low

TRUE

9

What is the route of infection of Francisella?

It gets in via an abrasion and goes to the LNs
Then migrates to liver, spleen, BM, forming granulomatous nodules which can ulcerate

10

What are the drugs you would use to treat Francisella?

Streptomycin or Gentomycin

11

What is the species of Coxiella we are concerned with?

Coxiella burnetii

12

Coxiella burnetii is an _________ bacterium that is closely related to _______ and Legionella

obligate intracellular
Francisella

13

Coxiella burnetii is the cause of ____ in humans and ______ in ruminants

Q fever
abortions and respiratory tract infections

14

What are the two phases of Coxiella burnetii and what is a unique feature of each?

Phase I: Highly infective
Phase II: less infective, appear when culutres are repeatedly passed through egg or tissue culture

15

Antibody against Phase ___ of Coxiella burnetii often appears first

II

16

What is the primary importance of disease for Coxiella burnetii? What do ruminants shed it in?

Contamination of meat/milk causing infection of humans
Ruminants shed it in milk, urine, feces, and esp the placenta

17

What causes Legionaire's disease?

Legionella pneumophila