MCBG - Intro To DNA Flashcards Preview

CJ: UoL Medicine Semester One (ESA1) > MCBG - Intro To DNA > Flashcards

Flashcards in MCBG - Intro To DNA Deck (16):
1

What is the width of a strand of DNA?

2 nanometres

2

What are the circular cores of nucleosomes called?

Histones

3

What is the name given to tightly ravelled nucleosomes?

Solenoids

4

What do genes carry?

The code for proteins. They have a chromosomal location.

5

How many chromosomes does a human have?

22 pairs plus two sex chromosomes, XX or XY

6

What is the difference between a nucleotide and a nucleoside?

Base + sugar + phosphate = nucleotide

Base + sugar = nucleoside

7

What are polynucleotides?

Linear polymers of nucleotides

8

What is the difference between the sugar on DNA and RNA?

On DNA is termed "deoxyribose" and has H on 2' carbon. On RNA has OH group and is termed "ribose".

9

What is the difference between a purine and a pyrimidine?

Purines have two rings, pyrimidines have one ring.

10

Which bases are purines?

Adenine and guanine

11

Which bases are pyrimidines?

Cytosine, uracil, thymine.

12

Which pair of bases has three hydrogen bonds rather than the usual two?

G-C

13

What catalyses DNA replication?

DNA polymerase

14

In which direction does DNA replication occur?

5' to 3'

15

What are Okazaki fragments?

Short sections of replicated DNA that form in the 5' to 3' direction on the lagging (top) strand during DNA replication.

16

What is used to join Okazaki fragments?

DNA ligase

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