Medications to treat Tardive Dyskinesia

Question 1

What is the primary purpose of medications used to treat Tardive Dyskinesia?

Answer 1

To manage and alleviate symptoms of Tardive Dyskinesia.

Question 2

Name a common generic medication used to treat Tardive Dyskinesia.

Answer 2

Valbenazine.

Question 3

What is the mechanism of action of Valbenazine?

Answer 3

Valbenazine is a vesicular monoamine transporter 2 (VMAT2) inhibitor.

Question 4

What is a potential adverse effect of Valbenazine?

Answer 4

Sedation.

Question 5

True or False: Valbenazine can cause weight gain.

Answer 5

True.

Question 6

What are common drug interactions with Valbenazine?

Answer 6

CYP2D6 inhibitors and CYP3A4 inhibitors.

Question 7

What is the generic name for the medication brand name Ingrezza?

Answer 7

Valbenazine.

Question 8

What is another medication approved for Tardive Dyskinesia?

Answer 8

Deutetrabenazine.

Question 9

What is the action of Deutetrabenazine?

Answer 9

It also inhibits VMAT2.

Question 10

List one adverse effect of Deutetrabenazine.

Answer 10

Drowsiness.

Question 11

True or False: Deutetrabenazine is not associated with akathisia.

Answer 11

False.

Question 12

What are the interactions of Deutetrabenazine?

Answer 12

CYP2D6 inhibitors.

Question 13

Fill in the blank: Tardive Dyskinesia is often caused by long-term use of __________.

Answer 13

antipsychotic medications.

Question 14

What symptom does Tardive Dyskinesia primarily involve?

Answer 14

Involuntary movements.

Question 15

What is the role of VMAT2 inhibitors in treating Tardive Dyskinesia?

Answer 15

They help to reduce excessive dopamine release.

Question 16

Name the two main medications used for Tardive Dyskinesia.

Answer 16

Valbenazine and Deutetrabenazine.

Question 17

What is one serious adverse effect that can occur with VMAT2 inhibitors?

Answer 17

Depression.

Question 18

True or False: VMAT2 inhibitors can be used in combination with antipsychotics.

Answer 18

True.

Question 19

What is the main benefit of using Valbenazine over other treatments?

Answer 19

It specifically targets Tardive Dyskinesia symptoms.

Question 20

How is Valbenazine administered?

Answer 20

Orally.

Question 21

What is the recommended starting dose for Valbenazine?

Answer 21

40 mg once daily.

Question 22

What should be monitored when a patient is on Deutetrabenazine?

Answer 22

Signs of worsening depression.

Question 23

Fill in the blank: Both Valbenazine and Deutetrabenazine are indicated for __________.

Answer 23

Tardive Dyskinesia.

Question 24

True or False: Tardive Dyskinesia symptoms can be irreversible.

Answer 24

True.

Question 25

What is the main concern when discontinuing antipsychotic medications in Tardive Dyskinesia patients?

Answer 25

Risk of exacerbating Tardive Dyskinesia symptoms.

Question 26

What age group is more susceptible to Tardive Dyskinesia?

Answer 26

Older adults.

Question 27

What is the effect of long-term antipsychotic use on dopamine receptors?

Answer 27

It can lead to supersensitivity of dopamine receptors.

Question 28

Name one non-pharmacological approach to managing Tardive Dyskinesia.

Answer 28

Cognitive Behavioral Therapy.

Question 29

True or False: Dietary changes can help alleviate Tardive Dyskinesia symptoms.

Answer 29

False.

Question 30

What is a common side effect of both Valbenazine and Deutetrabenazine?

Answer 30

Fatigue.

Question 31

What should be avoided when taking Valbenazine?

Answer 31

Alcohol.

Question 32

What is the importance of gradual dose adjustment in VMAT2 inhibitors?

Answer 32

To minimize the risk of adverse effects.

Question 33

Fill in the blank: The efficacy of Tardive Dyskinesia medications is generally assessed using __________ scales.

Answer 33

movement disorder.

Question 34

What is the trade name of Deutetrabenazine?

Answer 34

Austedo.

Question 35

How does Deutetrabenazine differ from Valbenazine?

Answer 35

Deutetrabenazine has a longer half-life.

Question 36

What is a key factor in the management of Tardive Dyskinesia?

Answer 36

Early detection and intervention.

Question 37

True or False: Tardive Dyskinesia can develop after a short duration of antipsychotic treatment.

Answer 37

False.

Question 38

What type of healthcare professional typically manages Tardive Dyskinesia treatment?

Answer 38

Psychiatrist.

Question 39

What is the role of patient education in managing Tardive Dyskinesia?

Answer 39

To inform about potential side effects and adherence to treatment.

Question 40

Fill in the blank: Tardive Dyskinesia is characterized by __________ movements.

Answer 40

repetitive, involuntary.

Question 41

What is the significance of monitoring for akathisia in patients taking VMAT2 inhibitors?

Answer 41

It can exacerbate anxiety and restlessness.

Question 42

True or False: Tardive Dyskinesia can only occur with typical antipsychotics.

Answer 42

False.

Question 43

What is the recommended follow-up frequency for patients on Tardive Dyskinesia medications?

Answer 43

Every 4-6 weeks initially.

Question 44

What is one potential long-term effect of untreated Tardive Dyskinesia?

Answer 44

Severe functional impairment.

Question 45

What is the primary neurotransmitter involved in Tardive Dyskinesia?

Answer 45

Dopamine.

Question 46

Fill in the blank: Tardive Dyskinesia symptoms may develop __________ after starting antipsychotic treatment.

Answer 46

months to years.

Question 47

What is the importance of a comprehensive treatment plan for Tardive Dyskinesia?

Answer 47

To address both motor and psychological symptoms.

Question 48

How can family support influence the management of Tardive Dyskinesia?

Answer 48

It can improve treatment adherence and emotional well-being.