Meds 2.0 Flashcards
(44 cards)
purpose of vancomycin
treats c.diff, and serious bacterial infections such as staph
classification of vancomycin
antibiotic - glycopeptide
mechanism of action for vancomycin
inhibits bacterial RNA and cell wall synthesis leading to cell death
side effects of vancomycin
ototoxicity
nephrotoxicity
GI upset
red man syndrome (IV infusion rxn): infuse slowly to avoid
phlebitis
interactions with vancomycin
NSAIDs, penicillins, aminoglycosides
contraindications with vancomycin
hypersensitivity to corn when given with dextrose soln
hypersensitivity to vancomycin
what to monitor for vancomycin
Therapeutic drug monitoring (TDM)
renal fxn: BUN, serum creatinine, GFR
CBC: anemia, thrombocytopenia (low platelets), leukopenia
electrolyte level
where is vancomycin cleared
in the kidneys
what is tobramycin used for
cystic fibrosis (respiratory system stuff)
eye infection
etc.
classification of tobramycin
antibiotic - aminoglycoside
mechanism of action for tobramycin
inhibits synthesis of bacterial walls by preventing protein synthesis
side effects for tobramycin
ototoxicity
nephrotoxicity
bronchospasms
GI upset
interactions with tobramycin
NSAIDs
vancomycin
other aminoglycosides
furosemide (loop diuretic)
anesthetics
where is tobramycin cleared
kidneys
what to monitor when taking tobramycin
electrolyte imbalances
nephrotoxicity: BUN, serum creatinine
contraindications for tobramycin
hypersensitivity to tobramycin, aminoglycosides, sodium bisulfate
category for acetaminophen
nonopioid analgesic, antipyretic
mechanism of action for acetaminophen
blocks prostaglandin - interfere with pain impulse & temp regulation in hypothalamus
side effects of acetaminophen
Hepatotoxicity
GI upset
decreased fertility
contraindications for acetaminophen
hypersensitivity
liver dysfxn (i.e. alcoholic)
antidote for acetaminophen
acetylcysteine (mucomyst)
interactions with acetaminophen
alcohol
what to monitor for acetaminophen
liver fxn: AST/ALT ratio (around 1.15), bilirubin (0.1-1.2 mg/dL), creatinine
category class of NSAIDs
nonopioid analgesic: anti-pyretic, antiplatelet, anti-inflammatory