Menti WS W9

Question 1

What is dihydroxylation?

Answer 1

two hydroxyl groups (–OH) are added to a carbon–carbon double bond (C=C), converting an alkene into a vicinal diol

Question 2

What is hydroxylation?

Answer 2

hydroxyl group (–OH) is introduced into an organic molecule. This transformation typically involves the conversion of a hydrogen atom (–H) into a hydroxyl group

Question 3

What is N – Dealkylation?

Answer 3

an alkyl group (such as –CH₃ or –CH₂CH₃) is removed from a nitrogen atom

Question 4

What is epoxidation?

Answer 4

alkene is converted into an epoxide

Question 5

What is O – Dealkylation?

Answer 5

alkyl group (like –CH₃ or –CH₂CH₃) is removed from an oxygen atom

Question 6

Which of the following conversions does not involve CYP enzymes?

O-dealkylation
N-dealkylation
Glucuronidation
N-oxidation
Epoxide hydrolysis

Answer 6

Glucuronidation and epoxide hydrolysis

Question 7

Why do patients become ill if they drink alcohol whilst taking metronidazole?

Answer 7

It inhibits aldehyde dehyrogenase