Energy balance and obesity W1 Flashcards
(29 cards)
Energy balance for weight loss
Less food intake and more energy expenditure (exercise)
Energy balance for weight gain
More energy intake and less energy expenditure
What percentage of energy intake is used for heat loss?
50%
What percentage of energy intake is for digestion/absorption?
5 to 10%
What is the rest of the energy intake used for?
ATP
physiological factors that regulate food intake
Hormones, peptides, energy stores, stomach distension, BG levels
Genetic factors that regulate food intake
Leptin, MC4R
Social factors that regulate food intake
Lifestyle, work
How many calories per day could produce 2 kg of weight gain per year?
50 kcal per day
What is leptin?
Sensor of body fat that reduces food intake And is produced by adipose issues
What are the two groups of neurons that have opposing actions in Lepton’s targets in the hypothalamus
Neuropeptide (NPY)and agouti related peptide (AGRP)
Pro-opiomelanocortin (POMC) and a-melanocyte-stimulating hormone (a-MSH)
Neuropeptide (NPY)and agouti related peptide (AGRP)
Work together to increase food intake and decrease energy expenditure
Energy in is increased energy out is decreased
You are more hungry
Activated by reduced leptin
Pro-opiomelanocortin (POMC) and a-melanocyte-stimulating hormone (a-MSH)
Work together to decrease food intake and increase energy expenditure
Leptin deficiency
Very rare
Genetic mutation
Diagnosed in childhood
No signal os always hungry
Severe early onset obesity
Resistance is more common
- level of leptin are high in obese but the brain stop responding to “I’m full” signals
Lipton levels linked with obesity
> fat = >leptin
What is BMR?
Basil, metabolic rate
The amount of energy suspended by the body to maintain physiological functions over a period of 24 hours
Inheritability of obesity
Can be as high as 30 to 40%
Gene disorders of obesity
Single gene disorders approximately 200 associated with obesity
Body mass index
Weight in kilograms/height in metres squared
Underweight BMI
< 18.5
Desirable BMI
18.5 to 24.9
Overweight BMI
25 to 29.9
Grade one moderately obese BMI
30 to 34.9
Grade 2 severely obese BMI
35 to 39.9