Inro To Cancer W5

Question 1

Emerging hallmarks

Answer 1

Avoiding immune destruction and deregulating cellular energetics

Question 2

Enabling characteristics

Answer 2

Team of promoting information and, genome instability and mutation

Question 3

Cancer linked to tobacco use

Answer 3

Lung, bladder, larynx, oesophagus, kidney, liver, pancreas, cervix

Question 4

Common sites and symptoms of cancer metastasis: brain

Answer 4

Headaches, seizure, vertigo

Question 5

Common sites and symptoms of cancer metastasis: respiratory

Answer 5

Cough, dyspnea, hemoptysis

Question 6

Common sites and symptoms of cancer metastasis: lymph nodes

Answer 6

Lymphadenopathy

Question 7

Common sites and symptoms of cancer metastasis: liver

Answer 7

Hepatomegaly

Question 8

Common sites and symptoms of cancer metastasis: skeletal

Answer 8

Pain, fracture, spinal cord compression

Question 9

What inhibitor is at each of the 6 hallmarks of cancer?

Answer 9

1. Sustaining signalling – EGFR.
2. Evade growth – CDK4
3. Activate invasion – MET.
4. Resist cell death – BCL2.
5. Enable immortality– telomerase
6. Induce angiogenesis – VEGF.