Metabolism, Nutrition, and Energetics Flashcards
(42 cards)
Subtrates
Substances acted on by an enzyme
Metabolism
Sum of all chemical and physical changes that occur in body tissues
Catabolism
Catabolic reactions
Convert large molecules into smaller ones
Anabolism
Anabolic reactions
Convert small molecules into larger ones
Nutrient pool
All the available nutrient molecules distributed in the blood
Catabolism of fats
Lipolysis
Fats > fatty acids and glycerol
Catabolism of carbohydrates
Glycogenolysis
Carbohydrates > glucose
Catabolism of proteins
Proteins > amino acids
What provides the energy for anabolism?
ATP from mitochondria
4 reasons cells synthesise new organic compounds
- Carry out structural maintenance or repairs
- To support growth
- To produce secretions
- To store nutrient reserves
Energetics
Flow of energy and its transformation from one form to another
Oxidation
Loss of electrons
Decrease in potential energy
Reduction
Gain of electrons
Increase in potential energy
Coenzyme
Acts as an intermediary that accepts electrons from one molecule and transfers them to another molecule e.g. NAD and FAD
Cellular respiration
glucose + 6 oxygen -> 6 carbon dioxide and 6 water
Glycolysis
The cell gains a net 2 molecules of ATP for each glucose molecule broken down anaerobically to 2 molecules of pyruvate. 2 molecules of NADH are also produced. In most cells, electrons are passed from NADH to FAD by an intermediate electron carrier in the intermembrane space, producing FADH2, and then to the electron transport chain
Citric acid cycle
Each of the two revolutions of the citric acid cycle required to break down the 2 pyruvate molecules completely yields 1 molecule of ATP by way of GTP. This cycling provides an additional gain of 2 molecules of ATP. This cycle transfers hydrogen atoms to NADH and FADH2. These coenzymes provide electrons to the electron transport chain
Electron transport chain
For each molecule of glucose broken down, a total of 10 NADH and 2 FADH2 deliver their high-energy electrons to the electron transport chain
Each NADH yields 2.5 ATP and each FADH2 yields 1.5 ATP. The 2 FADH2 molecules from glycolysis yield 3 ATP molecules and 2 water molecules. Each of the 8 molecules of NADH from the citric acid cycle yields 2.5 molecules of ATP and 1 water molecules. Thus, the shuffling from the citric acid cycle to the ETC yields 23 molecules of ATP
Gluconeogenesis
Formation of new glucose
Glycogenesis
Formation of glycogen (storage form of glucose)
Glycogenolysis
Breakdown of glycogen to glucose
Glycolysis
Breakdown of glucose to pyruvate
Beta-oxidation
Fatty acid molecules are broken down in a sequence of reactions into 2-carbon acetic acid fragments, and FAD and NAD+ are reduced
Lipogenesis
Synthesis of lipids