Microbio Week 11 - Rabies and other Zoonosis (Exam 3) Flashcards
(48 cards)
Unlike most viruses, what can rabies easily do?
Cross species
How is rabies transmitted?
Saliva in bite or scratch of infected mammal
T/F: Rabies is nearly 100% Fatal; only a few cases have survived
True
What are the primary carriers of rabies?
Raccoons
Bats
Skunks
The further the rabies virus needs to travel in the peripheral nervous system, the
longer the…
incubation time
Rabies virus moves faster once it reaches what?
Dorsal root ganglion
The closer the bite is to your brain, the shorter the…
incubation time
What is the first thing to do after exposure to rabies?
Wash wound with soap and water for 15 mins + dilute iodine if possible
What is the steps of rabies PEP?
- Human rabies IG injected into bite site
- Rabies vaccine given at different site and repeated on days 3, 7, 14
T/F: Rabies PEP is not that effective
FALSE, it is almost 100% effective
The rabies virus replicates in the muscle near the bite site and then enters where?
Nerves
Where is rabies PEP designed to prevent the virus from transferring?
To the nerves
What happens if the rabies virus makes it to the nerves?
It is hidden from immune system, travels to brain, and causes rabies
If you have the rabies vaccine and are exposed to rabies, what is the PEP?
Revaccination immediately
(no HRIG needed tho)
What family is hantavirus in?
Bunyavirus
What family is rabies in?
Rhabdovirus
What animals carry hantaviruses?
Wild rodents
Where is hantavirus excreted in rodents?
Urine
Feces
Saliva
Is hantavirus transmitted person to person?
NO
Does rabies have a viremic stage?
NO, even tho it is a generalized infection
(this is an exception)
Where do hantavirus transmission events occur?
Areas with rodent droppings
How does hantavirus transmission occur from rodent to person?
Breathing in droppings
Contaminated hands touching face
Bite
T/F: You should never sweep up or vacuum rodent droppings; instead, wet them with disinfectant, wait 10 minutes, and use gloves to clean them up
True
Does hantavirus cause disease in their rodent hosts?
No, but the rodent sheds the virus throughout their life
