Miller Flashcards Preview

D&T 3 test 2 > Miller > Flashcards

Flashcards in Miller Deck (32):
1

failure to complete separation from esophagus results in

TE fistula

2

what day does pulmonary arteries arise

44

3

what day are R and L bronchi present

28

4

when does pseudoglandular stage occur

5th to 17th week gestation

5

what is pseudoglandular stage

period of rapid branching of the pulmonary tree

6

when does canalicular stage occur

16-24 weeks

7

what is canalicular stage

- capillary bed expands and endothelium thins
- surfactant begin production

8

what accelerates tissue thinning and surfactant production

glucocorticoids

9

what is alveolar capillary dysplasia

capillary beds fail to form properly

10

when does saccular stage occur

28- 38

11

what happens in saccular stage

- decrease mesenchymal tissue
- increase type II cell

12

how does maternal diabetes impact baby

decreases surfactant production

13

when does alveolar stage occur

36- 2/3 yrs

14

what does pulmonary vascular change in alveolar stage

decrease smooth muscle
decrease pulmonary vascular resistance

15

what does VEGF do?

promotes angiogenesis

16

what does retinoic acid do

- increase alveolarization
- may decrease broncho pulmonary dysplasia

17

how does estrogen and testosterone change

estrogen: adequate levels of surfactant production
testosterone: slows lung development

18

surfactant protein A recycled by

type II pneumocyte

19

what is opsonin

phagocytosis and kills certain bacteria and fungi

20

can a baby still live with deficient surfactant protein A

yes

21

what is surfactant protein B required for

extra-uterine life

22

can a baby still live with deficient surfactant protein B

no

23

what activates surfactant protein C

SP-B

24

function of surfactant protein C

recruit phospholipids to lipid layers

25

can a baby still live with deficient surfactant protein C

yes

26

function of surfactant protein D

innate immunity

27

what increases surfactant secretion

glucocorticoids
estrogen
thyroid hormone

28

what decreases surfactant secretion

high levels of circulating insulin

29

how does Betamethasone impact lung development

increase surfactant production
decrease alveolar division
decrease alveolar length

30

what happens when Betamethasone is give to fetus

improves lung maturation

31

what happens when Betamethasone is give to mother

decrease fetal body

32

starburst fluid in lymphatic tissue

transient tachypnea of newborn
retained fetal lung fluid