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Misc Flashcards

(10 cards)

0
Q

Which bacterial toxins are encoded by a lysogenic phage?

A
ABCDE
shigA-like toxin
Botulinum toxin (certain strains)
Cholera toxin
Diphtheria toxin
Erythrogenic toxin of Strep. pyogenes
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1
Q

Patient with Hx of smoking presents with pneumonia, diarrhea, and confusion.

A

Legionella

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2
Q

Describe Listeria monocytogenes’ laboratory characteristics.

A

Gram (+) rods, catalase (+), non-sporulating

Characteristic tumbling motility. Actin rockets to move from cell to cell.

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3
Q

How is Listeria transmitted?

A

transmitted through unpasteurized milk, soft cheeses, deli meats, vaginal delivery.

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4
Q

Disease caused by Listeria in normal, healthy individuals

A

mild gastroenteritis

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5
Q

diseases caused by Listeria in pregnancy, neonates, immunocompromised pts?

A

Pregnancy: amnionitis, septicemia, spontaneous abortion.
Neonates: meningitis, granulomatosis infantiseptica
Immunocompromised: meningitis

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6
Q

Why does Listeria cause granuloma formation in infants?

A

Listeria is phagocytosed by MΦs, but prevents intracellular killing by escaping from the phagosome before fusion with the lysosome. Streptolysin O and phospholipase C allow this escape.

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7
Q

What Abx for Nocardia? Actinomyces?

A

oh, SNAP!
Sulfa drugs for Nocardia.
Actinomyces req’s Penicillin.

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8
Q

What does S. aureus’ Protein A do?

A

Binds Fc portion of Ig to prevent complement fixation and phagocytosis.

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9
Q

4 infections for which S. pneumoniae is the most common cause.

A
MOPS
Meningitis
Otitis media
Pneumonia
Sinusitis
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