Module 11 - Female Reproductive Flashcards

(55 cards)

1
Q

Organs of Female Reproduction

A

Organs of Female Reproduction
Ovaries – gonads
Uterine (Fallopian) Tubes
Uterus
Vagina
Vulva
Mammary Glands

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2
Q

Ovaries

A

Ovaries
Female gonads
Paired ovals – 2-3cm – size of almond
Upper pelvic cavity
Either side of uterus
Attached to uterus via ovarian ligament

Supported by Mesovarium
Extension of peritoneum
Connects to ovaries by broad ligament

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3
Q

Ovary Walls

A

Layers – superior to inferior
Ovarian Surface Epithelium – outer covering
Cuboidal epithelium

Tunia Albuginea
Dense connective tissue

Cortex - Ovarian Stroma

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4
Q

Cortex of Ovary

A

Cortex

Ovarian Stroma – Cell framework – bulk of ovary

Oocytes develop in outer layer
Surround by supporting cells
Follicle – oocyte & supporting cells
Mature follicle – expels a secondary oocyte – ovulation

Inner ovarian medulla
Blood and lymph vessels, & nerves

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5
Q

Oogenesis

A

Oogenesis
Egg development – creation of egg to maturation into a
cell that can be fertilized
Begins in fetal ovaries and continues till puberty
Fetal development – reduction division

After Puberty till menopause – equatorial division

Fertilization – maturation

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6
Q

Oogenesis - Fetal Development

A

Fetal development – reduction division
Ovarian stem cells – oogonia – in fetal ovaries

Divide by Mitosis – primary oocytes
Diploid – 46 chroms

Meiosis I begins for 1 cell
Arrests at Prophase I

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7
Q

Oogenesis - Puberty

A

After Puberty till menopause – equatorial division

Meiosis I resumes
2 cells made
1 haploid cell – most cytoplasm
Secondary oocyte – egg
Arrests at Metaphase II

1st Polar body
Makes 2 second polar bodies

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8
Q

Oogenesis - Fertilization

A

Fertilization – maturation
Stims Meiosis II to resume
Results
1 haploid cell
Polar body

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9
Q

Uterine Tubes

A

Uterine Tube
Fallopian tubes
Transport oocyte from ovary to uterus
Not directly connected to ovaries – peritoneal cavity

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10
Q

Sections of Uterine Tubes

A

Sections of Uterine Tubes
Medial to Lateral

Infundibulum – distal – flares out around ovaries
Finger projections – Fimbriae

Ampulla – middle – wide portion
Site of fertilization

Isthmus – narrow medial ends connecting to uterus

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11
Q

Walls of Uterine Tubes

A

Layers
Outer Serosa

Middle smooth muscle
High estrogen during ovulation stim contraction – peristaltic contractions

Inner mucosal layer
Ciliated cells – beat toward uterus – produce a current – push oocyte

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12
Q

Uterus

A

Uterus
Muscular organ
Nourishes and supports growing embryo
Transports sperm
Site of implantation of fertilized ovum
Muscles create contractions for labour
5cm wide by 7cm long – upside down pear shaped

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13
Q

Sections of Uterus

A

Sections

Fundus – superior – opening from uterine tubes

Body – middle

Cervix – inferior – projects into vagina
Secrets cervical mucus to protect sperm – helps it flow inside
Vagina is hostile – bacterial flora
Phagocytes want to get sperm – foreign substances

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14
Q

Walls of Uterus

A

Layers
Perimetrium – Serous Membrane
Epithelial tissue – covers exterior portion

Myometrium – smooth muscle layer
Responsible for contractions

Endometrium – inner
Lamina propria – connective tissue lining – lines lumen
Consists of two layers
Stratum basalis – basal layer
Stratum functionalis – functional layer

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15
Q

Uterus - Stratum functionalis

A

Stratum functionalis – functional layer
Thickens during ovulation
Sheds during menstruation
Site for implantation

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16
Q

Vagina

A

Vagina

Muscular canal
Entrance of repro tract
Passage way for: sperm – receives penis, menstrual flow, Baby – Lower portion of birth canal

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17
Q

Walls of Vagina

A

Walls
Outer fibrous adventitia

Smooth muscle layer

Inner mucous membrane
Transverse folds – rugae
Folds of skin – allow for stretch during intercourse and birth

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18
Q

Vulva

A

Vulva

Vulva or pudendum
External genital

Mons pubis – hairy fat pad – FUPA

Labia Major – hairy fat lips

Labia Minora – baby lips
protects female urethra
Entrance of repro tract

Clitoris – fun zone – lots of nerves
Encircled by labia minora

Hyman – thin membrane – partially covers entrance
Breaks

Bartholin’s (vestibular) Glands – lubricate vagina and vulva – either side

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19
Q

Mammary Glands

A

Mammary Glands
Accessory organ

Mammary glands – produces breast milk – modified sudoriferous sweat glands

Lie over pectoralis major and serratus anterior muscles

Growth hormone w/ other sex hormones – stim growth during puberty

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20
Q

Mammary Glands - Preggo Hormones

A

Hormones – during preggo
Estrogen – trigger growth

Progesterone - trigger growth

Prolactin – production - lactation

Oxytocin – release – muscles contraction

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21
Q

Lactation

A

Lactation
Synthesis milk
Secretion
Ejection to infant

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22
Q

Breast - External Features

A

External features

Nipple

Areola – surrounds nipple
Circular coloured area
Small, raised areola glands – secrete fluid – lube during lactation

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23
Q

Mammary Glands - Lactiferous Duct

A

Lactiferous duct – exit for milk – nipple
Connects internally – lactiferous sinus – drains milk from alveoli inside lobules
Baby draws milk by suckling

24
Q

Mammary Glands - Alveoli

A

Alveoli – milk secreting cells – clustered into lobules
Myoepithelial cells – surround alveoli
Contract and push milk out to sinus

25
Folliculogenesis
Folliculogenesis – ovarian follicle maturation into fertilization egg Works at the same time of Oogenesis Process from Primordial to secondary follicle continues after birth
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Folliculogenesis - Preantral Phase
Preantral phase – oocyte grows and differentiates
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Folliculogenesis - Ovulatory Stage
Ovulatory stage – follicle is ready to release a mature oocyte
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Folliculogenesis - Steps
Steps Primordial follicle Primary follicle Secondary Follicle Puberty Tertiary follicle – Antral Ovulating follicle – Mature Follicle – Graafian Corpus Luteum
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Folliculogenesis - Primordial follicle
Primordial follicle 10-30 recruited every month – fetal till puberty Granulosa cells – small – in patches
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Folliculogenesis - Primary Follicle
Primary follicle – growth Oocyte grows within Zona pellucida forms – membrane surrounds oocyte w/in Closes oocyte to more sperm entering – only 1 Granulosa cells surround – nurture – protect
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Folliculogenesis - Secondary Follicle
Secondary Follicle Oocyte bigger – primary oocyte still Zona pellucida there Granulosa cells – layers now Theca cells – develop on outside Structural support for follicle
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Folliculogenesis - Puberty
Puberty Gonadotropin releasing hormone – anterior pituitary gland Gonadotropins – LH & FSH Bind to receptors on secondary follicle Stim more differentiation to tertiary follicle Estrogen is released stops other follicles from starting Stops LH and FSH One takes all remaining estrogen – Atresia – death
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Folliculogenesis - Tertiary Follicle
Tertiary follicle – Antral Antrum develops – space b/w oocyte and granulosa cells Lots of estrogen – brain starts LH and FSH again
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Folliculogenesis - Ovulating Follicle
Ovulating follicle – Mature Follicle – Graafian Starts to break down the walls around oocyte Secondary oocyte at this point – Meiosis I – Prophase Continued too Metaphase II – pauses – waits for sperm Fertilized – Meiosis II continued
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Folliculogenesis - Corpus Luteum
Corpus Luteum – follicle has releases oocyte – left over tissue cells
36
Menstrual Cycle
Menstrual Cycle – Uterine Series of changes – Uterine lining sheds, rebuilds, and prepares for implantation Average 28-day cycle Phases Menses Proliferative Secretory
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Menstrual Cycle - Menses
Menses – day 1 – Lining is shed Shedding of Stratum Functionalis of endometrium Early days of follicular phase Secondary follicle begins to develop Progesterone, FSH, and LH are low Decline in progesterone triggers shedding Degradation into corpus luteum – end of luteal phase
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Menstrual Cycle - Proliferative
Proliferative – flow stops day 6-13 Granulosa and Theca cells of Tertiary (Antral) Follicle produce estrogen Stims endometrial lining to rebuild Follicle stims LH to trigger ovulation Ovulation marks end of phase – day 14
39
Menstrual Cycle - Secretory Phase
Secretory Phase – prepares for implantation In ovaries – Luteinisation – mature follicle – oocyte release – follicle turns to corpus luteum In uterus – progesterone from corpus luteum begins phase Endometrial glands secrete fluid rich in glycogen Arteries develop to increase blood for thickening of walls – stratum functionalis
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Menstrual Cycle - If not preggo
If no preggo Corpus luteum will degrade into corpus albicans Estrogen and progesterone fall Blood reduces Endometrial tissues die – menses
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Hormones of Reproductive Cycles
Hormones Hypothalamus releases gonadotropin-releasing hormone (GnRH) Stims Anterior Pituitary Gland to release FSH and LH Estrogen Progesterone Relaxin Inhibin
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FSH
FSH Stims development of follicle Stims secretion of estrogen by ovaries
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LH
LH Stims further development of follicles Ovulation Secretion of estrogen and progesterone
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Estrogen
Estrogen Preps endometrium Promotes development and maintenance of repro structures Secondary sex characteristics Breast Regulates fluid and electrolyte balance Stims protein synthesis Moderate levels inhibit hypothalamus release of GnRH
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Progesterone
Progesterone Works with estrogen to prep endometrium Preps mammary glands for milk synthesis
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Rexalin
Relaxin Inhibit contractions of uterus – makes it easy for ovum to implant Preggo – dilates the cervix for delivery
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Inhibin
Inhibin Inhibits secretion of FSH & GnRH Decreases FSH and LH at end of uterine cycle
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Hormonal Birth Control
Hormonal Birth Control Birth Control contains synthetic estrogen and progestins Estrogen and progesterone suppress FSH and LH Mimic hormonal state after ovulation – tricks ovaries – ovulation has occurred Constant suppression Keeping high levels will stop FSH and LH from triggering ovulation Prevents pregnancy
49
Hormonal Birth Control - Prevents Preggo by?
Prevents pregnancy Stops ovulation – prevents release of eggs from ovaries Thickens cervical mucus – sperm can’t reach Thin uterine lining – fertilized egg can’t implant
50
Coitus
Coitus Sexual intercourse – copulation Process where spermatozoa is deposited into the vagina
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Reproductive Cycle - 4 Phases
4 Phases Menstrual Cycle Proliferative Phase Ovulation Postovulatory Phase
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Reproductive Cycle - Menstrual Phase
Menstrual Cycle Small secondary oocytes begin development Stratum functionalis sheds
53
Reproductive Cycle - Proliferative Phase
Proliferative Phase Primary follicles develop into secondary follicles Atresia for all except 1 (sometimes more) Remaining follicle develops into Graafian (Mature) Follicle Increases estrogen production w/ increasing levels of LH Endometrium repair
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Reproductive Cycle - Ovulation Phase
Ovulation Mature Oocyte is released from follicle LH surges Follicle becomes corupus luteum – stim’ed by LH – continued production of estrogen Helping uterus prep for fertilization
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Reproductive Cycle - Postovulatory Phase
Postovulatory Phase – day 15-28 – secretory phase in uterus Active endometrial glands – thickening walls Anticipating implantation Fertilized by sperm Corpus luteum gives nutrients till placenta develops Secrets hormones to support preggo and breast development