Flashcards in Molluscicide Deck (32)
What is an example of a restricted pesticide used alone or in combination with other compounds as a molluscicide?
Outside of North America what is metaldehyde used as?
Fuel for camp stoves.
What is the most common form of exposure for metaldehyde?
Ingestion of baits
What are 4 forms metaldehyde can come in?
What percentage concentration of metaldehyde is allowed in the US?
What is a polymer of acetaldehyde that is a flammable irritant?
Is metaldehyde soluble in water?
Products can release metaldehyde for how long under moderately moist conditions?
What are 4 species of animals susceptible to metaldehyde toxicity?
Which are more sensitive to metaldehyde toxicity, cats or dogs?
Which animals is more likely to ingest metaldehyde, a dog or a cat?
Metaldehyde is more toxic through what route of exposure?
Which route is more common?
In what type of environment does metaldehyde undergo acid hydrolysis to acetaldehyde?
Where is metaldehyde readily absorbed from in the body?
Does Metaldehyde cross the BBB?
What is an example of a molluscicide?
Where is metaldehyde metabolized?
What might decrease the toxicity of metaldehyde?
What is an example of one?
- Enzyme inducer
What is acetaldehyde metabolized by?
What is it converted to?
Then what happens?
- Hepatic aldehyde dehydrogenase
- Converted to CO2
Can metaldehyde undergo enterohepatic recirculation?
Metaldehyde decreases brain concentrations of what 3 neurotransmitters?
- Serotonin (5-HT)
If GABA is decreased, What are 2 examples of CNS signs that might occur?
- CNS excitation
How is metaldehyde responsible for the breakdown of 5-HT and norepinephrine, thus reducing their levels?
By increasing MAO
What are 2 GI/systemic signs that metaldehyde can cause?
- GI irritation
- Metabolic acidosis
What can CNS excitation lead to?
What is often the cause of death with metaldehyde toxicosis?
Dogs that survive acute metaldehyde toxicosis may develop what?
Has this been reported in cats?
- Liver failure
The "shake and bake" seen with metaldehyde toxicosis refers to what 2 clinical signs?
- Acute neurotoxicosis
Onset of clinical signs with metaldehyde toxicosis are usually seen when?
Within 3 hours
What are 3 GI signs that can be seen with metaldehyde toxicosis?
Incoordination, muscle tremors, hyperesthesia, convulsive seizures and opisthotonos are CNS signs that can be seen with what type of toxicosis?