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Flashcards in Molybdenum Toxicosis Deck (25):
1

What are 2 potential sources of molybdenum toxicosis?

- Excess molybdenum
- Copper deficiency

2

What are 4 potential sources of excess molybdenum?

- Soil rich in/contaminated with molybdenum
- Plants can accumulate molybdenum from soil
- Industrial contamination
- Molybdenum-containing fertilizers

3

What are 4 states that can have soil rich in molybdenum?

- Florida
- California
- Oregon
- Nevada

4

Is molybdenum an essential trace element?

Yes

5

Molybdenum is a component of what?
Which converts what to what?

- Xanthine oxidase
- Converts purine xanthine to uric acid

6

What does elevated molybdenum interfere with?

Copper absorption

7

What does excess molybdenum cause?

Copper deficiency

8

Which species is most susceptible to molybdenum toxicosis?
Toxicosis has been seen in what other species?

- Cattle
- Sheep

9

Which 2 species are resistant to molybdenum toxicosis?

- Horses
- Pigs

10

What can increase molybdenum toxicity?

High levels of dietary sulfate

11

What can decrease molybdenum toxicity?

Dietary copper

12

What is the maximum tolerable dietary level of molybdenum?

5-10 ppm

13

Where is molybdenum absorbed?

GI tract

14

Where can molybdenum be excreted at toxic levels?

Milk

15

What can cause molybdenum toxicosis?

Copper deficiency

16

What is an element that is involved in hematopoeisis, connective tissue metabolism, myelin formation in newborn animals, pigmentation and bone formation?

Copper

17

Which element is a component in essential enzymes such as cytochrome oxidase and aromatic amino acid-metabolizing enzymes (tyrosinase, dopamine hydroxylase, MAO)?

Copper

18

Copper-containing proteins (cupreins) inmost aerobic cells have what?

Superoxide dismutase activity

19

What clinical sign can be seen 8-10 days following molybdenum toxicosis exposure?

Severe diarrhea (greenish with fluids and gas bubbles)

20

What are 2 other clinical signs that can be seen with molybdenum toxicosis?

- Rough hair coat
- Depigmentation of hair, especially around eyes

21

Loss of weight, anemia, osteoporosis and exotosis, lameness and pica are clinical signs seen with which toxicosis?

Molybdenum toxicosis

22

What is a clinical sign of molybdenum toxicosis seen in bulls?
In cows?

- Bulls: Decreased libido
- Cows: Infertility

23

What is considered an elevated molybdenum level in the blood?
The liver?

- >0.1 ppm
- > 5 ppm

24

Copper levels below what in the blood can lead to molybdenum toxicosis?
In the liver?

-

25

What are 2 forms of treatment for molybdenum toxicosis?

- Copper glycinate SC
- Copper sulfate added to diet