Flashcards in [Multiple Sclerosis] Deck (25)
[MS]: ... levels relate to prevention of MS and fewer lesions in those already diagnosed
[MS]: what is the ocular involvement
Unilateral optic neuritis
[MS]: What are the 4 main symptoms classical to MS
Diplopia/ataxia (brainstem/cerebellar involvement)
[MS]: Poor prognosis is associated with increased age, ... gender, early motor involvement and many lesions.
[MS]: Dx is clinical and is upon what observation
lesions disseminated in time and space unattributable to another cause
[MS]: How might an unnoticed previous demyelinating lesion manifest.
Brief period of visual disturbance, unexplained.
[MS]: What is the name of the set of criteria used for aiding Dx
[MS]: What disease may also present with an inflammatory demyelination
(aka neuromyelitis optica)
[MS]: Is Devics or MS associated with more severe attacks
[MS]: Where are the MRI cord lesions in MS
peripheral (multiple and small)
[MS]: In Devics where are the cord lesions
Continuous and long
[MS]: Devics is differentiated from MS by the detection of ... antibodies
Anti-AQP4 (NMO-IgG: aka)
[MS]: What lifestyle advice do you give (1)
Stress reduction (reduced new lesions incidence)
[MS]: if you suspect the pt of low levels of sun exposure you give ...
[MS]: 1st line Tx for an acute relapse is ...
Methylprednisolone (for <3days)
[MS]: Up to how many times can you give steroid in 1 year for treatment for an acute relapse
2 (due to SE)
[MS]: In relapsing-remitting MS what what 2 mAbs are used
[MS]: ... in CSF (and not in serum) is indicative of some sort of CNS inflammation
Oligoclonal IgG bands
[MS]: How does geography affect prevalence of MS
More common the further away from the equator.
[MS]: How does temperature affect the disease
Worse at higher temperatures (bath/warm)
[MS]: How might visual evoked potentials aid in diagnosis
indicates optic nerve damage
[MS]: Tx: Interferons .... and .... reduce relapse and lesion accumulation (no effect on prognosis)
[MS]: how does optic neuritis present? (2)
decreased central vision
pain on movement
[MS]: what 2 things may trigger a worsening of symptoms
heat (e.g. hot bath)