Flashcards in [parkinsonisms] Deck (32)
[parkinsonism]: what is the cardinal triad
[parkinsonism]: when would you see the tremor
tremor at rest
[parkinsonism]: what characteristic movement of the hand is associated with tremor
[parkinsonism]: how would facial hypokinesia manifest
[parkinsonism]: repetitive movements manifest their hypokinesia with ...
decreased amplitude of movement
[parkinsonism]: which category of drugs can cause parkinsonism
[parkinsonism]: 2 specific drugs that can cause
Metoclopramide (D-R antagonist)
Prochlorperazine (D-R2 antagonist)
[parkinsonism]: accumulation of what metals can cause parkinsonism (2)
[PD]: Typical age of onset
[PD]: pathology of PD?
Mitochrondrial DNA dysfunction
degeneration of dopaminergic neurons in substantia nigra pars compacta
(associated with Lewy bodies)
[PD]: dopamine therapy length of tx before end of dose dyskinesias and wearing off?
[PD]: 1st line dopamine agonists (early stage of PD)
[PD]: For sudden 'off' freezing, what medical Tx (in 'rescue-pen' form) is used?
[PD]: non-motor features? (3)
reduced sense of smell
[PD]: Prosody may be present. What is it?
poor emotional content of speech decoding
[PD]: Poor simultaneous cognitive and motor function can manifest as
Freezing whilst walking
[PD]: MAO-B inhibitors are an alternative to DAs in early PD. Name 2.
[PD]: What drug may be used to lessen end-of-dose wearing? (2)
[PD]: What is the major complication with COMTi
[PD]: Drug Tx for tremor (2)
[PD]: Major SE of anticholinergics
Confusion in elderly
[PD]: Levodopa is prescribed with what dopa-decarboxylase i
[PD]: depression/dementia/psychosis are common, what 2 causes may these be from
[PD]: SE of Levodopa/carbidopa is Nausea. What can be prescribed?
[PD]: Parkinsons Plus syndromes have 5 red flags. What is them mneumonic?
[PD]: Parkinson plus syndomes disease: postural instability
progressive supra nuclear palsy
[PD]: Parkinson plus syndomes disease: autonomic features
Multi system atrophy
[PD]: Parkinson plus syndomes disease: fluctuating cognition
Lewy body dementia
[PD]: Parkinson plus syndomes disease: rigidity/apraxia
[PD]: Parkinson plus syndomes disease: pyramidal signs
[PD]: Deep brain stimulation may be used in Pts who ..
partly dopamine responsive