Flashcards in [Myaesthenia Gravis] Deck (33)
[MG]: What might be noticed on smiling
(preserved vertical but decreased horizontal excursion of lips)
[MG]: how might you elicit the increasing muscular fatigue
voice fades on counting to 50
[MG]: how are tendon reflexes affected
Tendon reflexes normal
[MG]: Under the age of 50 MG is associated with (2)
[MG]: Over the age of 50 MG is associated with (2)
[MG]: Antibodies are directed against ...
nicotinic acetylcholine receptors
[MG]: Which symptoms are usually first noticed
ocular muscle fatigue
[MG]: What is the peek sign indicative of
Shows orbicularis fatigue
[MG]: What antibodies are present in 90%
[MG]: if Mg is confined to the eyes anti-AchR is only ...%
[MG]: If seronegative for AchR which antibodies do you check for
MuSK (muscle specific tyrosine kinase)
[MG]: In a MG +ve pt what would repetitive nerve stimulation show
Decremental muscle response
[MG]: Ice application to the shut affected ptotic eye for 2 mins may improve ptosis by ... mm
[MG]: What imaging would you request
CT of thymus
[MG]: Symptomatic Tx is ...
[MG]: 1st line Tx for relapses is ...
[MG]: How often should the patient receive immunosuppressive drugs
[MG]: What should be co-prescribed with the 1st line drug
[MG]: ... once a week can be prescribed along side steroids tx
[MG]: ... daily can be prescribed along side steroids tx
[MG]: If anticholinesterases do not control symptoms and the pt is <50, what Tx option is there
[MG]: What is the major worry
respiratory muscle fatigue during relapse
[MG]: how can you monitor for the main worry in MG patients
Forced vital capacity
[MG]: if starting azathioprine what should be checked weekly fror 8 weeks then 12-weekly (2)
[MG]: involvement of muscel groups starts at ... and ends with .. muscle involvement
(bulbar, face, neck, limb)
[MG]: pyridostigmine SEs i.e. cholinergic (3)
[MG]: 5 days pre-op to thymectomy what may be give
[MG]: Myasthenic crisis is the major medical concern. What is it.
life threatening weakness of respiratory muscles in relapse
[MG]: What is the FVC for ventilatory support
[MG]: Tx for myasthenic crisis (2)
[lambert-eaton}: what is the difference in presentation between MG and LE myasthenic syndrome?
gait difficulty before eye signs
[lambert-eaton}: what is the pathophysiological cause of LES?
Antibodys against pre-synaptic membrane Calcium voltage channels