Mycology I Flashcards

(48 cards)

1
Q

dimorphic fungi at temp

A

cold - mold
heat - yeast

except cocidiomycosis - spherule in tissue

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2
Q

tx for local mycosis infection

A

flucanozole

itraconazole

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3
Q

tx for systemic mycosis infection

A

amphotericin B

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4
Q

mississippi and ohio river valley, pneumonia, macrophage filled

A

histoplasmosis

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5
Q

histoplasmosis

A

mississippi and ohio river valley

fills macrophages

bird and bat poo

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6
Q

blastomycosis

A

east of mississippi river and central america

inflammatory lung disease - disseminate skin and bone

granuloma nodules form

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7
Q

coccidiomycosis

A

southwest US, Cali

pneumonia and meningitis

increased rate after earthquake - dust to air

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8
Q

spherule filled with endosores

A

coccidiomycosis

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9
Q

captains wheel formation

A

paracoccidiomycosis
in latin america

budding yeast

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10
Q

cutaneous mycosis

A

tinea

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11
Q

cutaneous fungal infection

A

dermatophyte

tinea

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12
Q

dermatophytes

A

cause tinea

microsporum, trichophyton, epidermophyton

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13
Q

microsporum

A

dermatophyte - cutaneous fungal infection

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14
Q

trichophyton

A

dermatophyte - cutaneous fungal infection

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15
Q

epiermophyton

A

dermatophyte - cutaneous fungal infection

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16
Q

tinea capitis

A

head/scalp fungal infection

dermatophyte

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17
Q

tinea corporis

A

body fungal infection

dermatophyte

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18
Q

tinea cruris

A

inguinal area fungal infection

dermatophyte

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19
Q

tinea pedis

A

foot fungal infection

3 varieties:
1 interdigital MC
2 mocassin
3 vesicular

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20
Q

tinea unguium

A

nailbed fungal infection

aka onychomycosis

21
Q

onychomycosis

A

nailbed fungal infection

tinea unguium

22
Q

tinea versicolor

A

from malassezia species

-yeast like fungus

23
Q

tinea versicolor path

A

degradation of lipid produces acids - damage melanocytes
-reults in hypopigmented and pink patches

often in summer and hot-humid weather

24
Q

spaghetti and meatballs on microscopy

A

tinea versicolor - malassezia

25
oral thrush
candida in immunocompromised
26
endocarditis in IV drug user
candida
27
tx of candida
topical azole - vaginal nystatin, flucanozole, or caspofungin - oral thrush flucanozol, caspofungin, ampho B - systemic
28
germ tube at 37C
candida albicans
29
pseudohyphae and budding yeast at 20C
candida albicans
30
septate hyphae branch at 45 egrees
aspergillus fumigatus
31
aspergilloma
in lung cavity - after TB
32
aflatoxins
produced by aspergillus species | -associated with hepatocellular carcinoma
33
allergic bronchopulmonary aspergillosis
asthma and CF association bronchiectasis and eosinophilia
34
india ink stain with halos
cryptococcus neoformans
35
cryptococcus neoformans
heavily capsuled yeast | -soil and pigeon droppings
36
pigeon droppings
cryptococcus neoformans
37
sabouraud agar
culture of cryptococcus neoformans
38
soap bubble lesion in brain
cryptococcus neoformans
39
mucormycosis
diabetic ketoacidosis mucor and rhizopus specie fungi proliferate blood vessel wall - penetrate cribriform plate - enter brain rhinocerebral frontal lobe abscess HA, facial pain, black necrotic eschar on face
40
tx of mucormycosis
surgical debridement | amphotericin B
41
pneumocystis pneumonia
diffuse interstitial pneumonia -with pneumocystis jirovecii get disease if immunosuppressed (ex/ AIDs)
42
CXR for pneuomcystis pneumonia
B/L ground glass opacities diagnosis - lung biopsy or lavage
43
disc shaped yeast on methenamine sliver stain
pneumocystic jirovecii
44
tx pneumocystis jirovecii
TMP-SMX pentamide dapsone (prophylaxis) atovaquone (prophylaxis)
45
prophylaxis in HIV for pneumocystis
dapsone and atovaquone if CD4
46
rose gardener gets pustule and ulcer along lymphatics
sporothrix schenckii
47
sporothrix schenckii
dimorphic | cigar shaped budding yeast
48
tx sporothrix
itraconazole | potassium iodide