Virology II

Question 1

genital herpes

Answer 1

HSV-2

Question 2

neonatal herpes

Answer 2

HSV-2

Question 3

chickenpox and shingles

Answer 3

HSV-3

varicella zoster

Question 4

latent varicella zoster

Answer 4

in dorsal root or trigeminal ganglia

HSV-3

Question 5

mononucleosis

Answer 5

EBV - HSV-4

Question 6

mechanism of EBV infection

Answer 6

through CD21

Question 7

monospot test

Answer 7

detect EBV

heterophile antibody

Question 8

heterophile antibody

Answer 8

monospot test

Question 9

burkitt lymphoma and nasopharyngeal carcinoma

Answer 9

EBV virus - HSV-4

Question 10

mononucleosis with negative monospot

Answer 10

CMV

Question 11

owl inclusion inclusion

Answer 11

CMV

Question 12

roseola

Answer 12

HHV-6/7

seizure, diffuse macular rash

saliva transmission

Question 13

tzanck test

Answer 13

detect multinucleated giant cells
-commonly seen in HSV-1,2,3

3 = VZV

also see intranuclear inclusions

Question 14

reovirus

Answer 14

RNA virus
no envelope
DS linear
icosahedral double capsid

Question 15

coltivirus and rotavirus

Answer 15

reoviruses

Question 16

picornaviruses

Answer 16

ssRNA
linear positive strand
no envelope
icosahedral capsid

Question 17

poliovirus

Answer 17

picornavirus

salk/sabin vaccines

Question 18

rhinovirus

Answer 18

picornavirus

Question 19

coxsackievirus

Answer 19

picornavirus

Question 20

PERCH viruses

Answer 20

picornaviruses

poliovirus
echovirus
rhinovirus
coxsackievirus
hep A virus

Question 21

hepatitis A virus

Answer 21

picornavirus

Question 22

hep E virus

Answer 22

hepevirus

Question 23

hepevirus

Answer 23

ss positive RNA
no envelope
icosahedral

Question 24

hepatitis C virus

Answer 24

flavivirus

Question 25

yellow fever

Answer 25

flavivirus

Question 26

dengue

Answer 26

flavivirus

Question 27

west nile virus

Answer 27

flavivirus

Question 28

rubella

Answer 28

togavirus

Question 29

HIV

Answer 29

retrovirus ss positive RNA enveloped complex and conical capsid

Question 30

common cold

Answer 30

coronavirus ss postitive RNA

Question 31

influenza virus

Answer 31

orthomyxoviurs

Question 32

paramyxovirus

Answer 32

parainfluenza RSV measles mumps PRMM

Question 33

rabies

Answer 33

rhabdovirus ss negative linear RNA virus enveloped helical capsid

Question 34

hepatitis D virus

Answer 34

delta virus

Question 35

norovirus

Answer 35

viral gastroenteritis calcivirus ss positive sense RNA icosahedral capsid

Question 36

hep D

Answer 36

requires hep B

Question 37

negative strand viruses

Answer 37

need to transcribe to positive virion brings its own RNA dependent RNA polymerase ``` arenavirus bunyavirus paramyxovirus orthomyxovirus arenavirus reovirus ```

Question 38

runny nose

Answer 38

rhinovirus - nonenveloped RNA virus picornavirus >100 serologic subtypes acid labile - destroyed stomach acid does not infect GI tract

Question 39

yellow fever

Answer 39

flavivirus aedes mosquito

Question 40

high fever, black vomit, jaundice, councilman bodies, liver bx

Answer 40

yellow fever virus infection

Question 41

councilman bodies

Answer 41

eosinophilic apoptotic globules

Question 42

rotavirus

Answer 42

most important global cause of infantile gastroenteritis segmented dsRNA virus

Question 43

influenza

Answer 43

negative sense ssRNA - 8 segment genome orthomyxovirus

Question 44

flu shot

Answer 44

viral strain