Mycoplasma I & II (Exam 2) Flashcards

(55 cards)

1
Q

Mycoplasma lack a cell wall, so they have no ___________.

A

peptidoglycan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Mycoplasma have a single walled membrane made of ____________.

A

cholesterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

(T/F) Mycoplasma are more genetically similar to gram-negative bacteria and stain pink.

A

False - gram-positive but stain pink (lost peptidoglycan)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Mycoplasma are (facultative/obligate) parasites.

A

obligate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Mycoplasma are obligate parasites because they cannot make _________ and _________, which they must steal from the host.

A

pyridines
pyrimidines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How does Mycoplasma appear on culture?

A

fried egg appearance (small colonies)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

(T/F) Mycoplasma is pleomorphic.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Mycoplasma makes high levels of what substance which is toxic to eukaryotic cells?

A

hydrogen peroxide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the oxygen requirement of Myoplasma?

A

facultative anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Do Mycoplasma have endotoxin? Exotoxins?

A

No endotoxin
Only 2-3 species make exotoxins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Disease caused by Mycoplasma infection typically causes __________ reactions.

A

fibrinous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

(T/F) Mycoplasma usually infects the GI tract.

A

False - usually NOT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

List 5 common tissues that Mycoplasma infects.

A
  1. serous surfaces
  2. respiratory tract
  3. mammary glands
  4. genitals
  5. circulatory system
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Mycoplasma pneumoniae causes what disease in humans, specifically teens?

A

Primary Atypical “Walking” Pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Serology is commonly used to diagnose Mycoplasma infection. This is done via what process?

A

complement fixation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What does a positive complement fixation result mean in a serology test for Mycoplasma?

A

no RBC lysis (mycoplasma antibodies present)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What does a negative serology result for complement fixation indicate for Mycoplasma?

A

RBC lysis occurs (no antibodies against Mycoplasma)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

In terms of antibiotic treatment, drugs with what mechanism usually work against Mycoplasma?

A

protein-synthesis inhibitor antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What 3 major antibiotics is Mycoplasma resistant to due to its structure?

A

Beta-lactams
Vancomycin
Bacitracin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

(T/F) Most Mycoplasma are species-specific.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Mycoplasma mycoides subspecies mycoides causes what disease?

A

Contagious Bovine Pleuropneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

In Contagious Bovine Pleuropneumonia, Mycoplasma mycoides subspecies mycoides usually colonizes (one/both) lung(s).

A

one lung

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Contagious Bovine Pleuropneumonia has a (low/high) morbidity and mortality.

24
Q

(T/F) Mycoplasma mycoides subsp. capri is the most important cause of death in cattle.

A

False (subsp. mycoides)

25
Mycoplasma bovis primarily infects ________ cattle.
dairy
26
What disease does Mycoplasma bovis cause in cattle and bison?
Severe Epizootic Mastitis
27
List a few clinical signs of Mycoplasma bovis infection (Severe Epizootic Mastitis).
1. polyarthritis 2. respiratory disease 3. swollen udders 4. agalactia ("dry up") 5. abnormal milk secretions
28
How is M. bovis transmitted?
milking (teat canal)
29
Severe Epizootic Mastitis caused by Mycoplasma bovis can be part of a larger collection of bacterial and viral infections called:
BRDC
30
Which two species are affected by Mycoplasma mycoides subsp. capri?
sheep & goats
31
What 3 disorders does Mycoplasma mycoides subsp. capri cause?
1. mastitis 2. polyarthritis 3. pneumonia
32
Only goats are affected by Contagious Caprine Pleuropneumoniae. Which bacterial species causes this disease?
Mycoplasma capricolum capripneumoniae
33
(T/F) Contagious Caprine Pleuropneumoniae is a signficiant disease affected goats populations in the US.
False - NOT in US
34
Mycoplasma ___________ causes pneumonia in sheep and caused massive death of "big horn sheep" in the US.
ovipneumoniae
35
All Mycoplasma species with the prefix hyo- only affect which species?
pigs
36
Which two species of Mycoplasma cause polyarthritis in swine?
M. hyorhinis M. hyosynoviae
37
In addition to polyarthritis, Mycoplasma hyorhinis causes what two other diseases in pigs?
polyserositis pneumonia
38
(T/F) Mycoplasma hyorhinis is in the normal flora of the swine nasal cavity.
True
39
Mycoplasma hyosynoviae causing Polyarthritis in swine is (erosive/non-erosive) and therefore, (fibrosis/no fibrosis) occurs.
non-erosive no fibrosis
40
When should you treat for Mycoplasma hyosynoviae (Polyarthritis in swine)?
Early! (first 24 hours)
41
Which species of Mycoplasma causes Swine Enzootic Pneumonia?
M. hyopneumoniae
42
Mycoplasma hyopneumoniae in pigs has a (high/low) mortality and binds to ________ in the upper respiratory tract.
low cilia
43
As Bordetella bronchiseptica initiates PRDC complex, _________ _________ initiates MIRD complex in swine.
Mycoplasma hyopneumoniae
44
What disease is caused by Mycoplasma suis in pigs?
Eperythrozoonosis
45
What is the most important avian Mycoplasma species?
M. gallisepticum
46
Mycoplasma gallisepticum causes ____________ in chickens and ___________ in turkeys.
Chronic Respiratory Disease Infectious Sinusitis
47
How is M. gallisepticum transmitted?
aerosols or transovarian
48
Mycoplasma gallisepticum uses ____________ to turn on and off surface proteins, via phase variation.
haemagluttinins
49
Tenosynovitis, arthritis, and respiratory disease, and Eggshell Apex Abnormality in birds are all caused by Mycoplasma __________.
synoviae
50
What are the 3 clinical signs are seen in a bird infected with Mycoplasma synoviae?
1. joint lameness 2. URI 3. "weakening" of eggshells
51
Which Mycoplasma infects turkeys causing air sacculitis, bone deformities, reduced growth, and genital tract infection?
Mycoplasma meleagridis
52
Mice and rats develop chronic respiratory disease by Mycoplasma ___________.
Mycoplasma pulmonis
53
(T/F) Mycoplasma pulmonis infection of mice and rats is subclinical until a stressor triggers chronic respiratory disease.
True
54
Which Mycoplasma species contributes to Canine Infectious Respiratory Disease Complex in dogs?
Mycoplasma cynos
55
Unlike Mycoplasma, the genus Ureaplasma have the enzyme:
urease