Neonatal infections / TORCHES Flashcards Preview

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Flashcards in Neonatal infections / TORCHES Deck (49):
1

what constitutes a peri natal infection

infections acquired before (in utero), during (natal), or shortly after birth (post-natal)

2

what is the MCC of perinatal infection

CMV

3

intracranial calcification

toxo (diffuse) or CMV (periventricular)

4

Chorioretinitis

Toxo or CMV

5

Cataracts

Rubella or HSV

6

congenital cardiac dz

Rubella

7

Bone lesions

Syphilis (saber shins) or rubella

8

vesicles

HSV, VZV, or syphilis

9

Microcephaly

CMV

10

Hydrocephalus

Toxo

11

how do you prevent toxoplasmosis

avoid cat litter and undercooked beef

12

presents w/ chorioretinitis, hydrocephalus, and intracranial calcifications

Toxo

13

how do you dx toxo

serology

14

what is the MC meningitis infection in babies

GBS

15

how do you decrease risk of GBS infection

intrapartum abx

16

How does GBS infect the baby

vertical transmission

17

mom has arthritis

Rubella

18

PDA, cataract, deaf, blueberry rash

Rubella

19

what causes rubella

togavirus

20

hearing loss, blueberry rash and seizures

CMV

21

what is the worst CMV infection

congenital > natal> postnatal

22

how do you tx CMV

IV ganciclovir

23

how do you dx CMV

CMV isolation from body fluids

24

CMV is what type of virus

HHV5 dsDNA linear and enveloped

25

what type of virus is HIV

ssRNA+ w/ RT

26

how do you dx HIV

viral culture + PCR

27

what is the tx @ birth of HIV

AZT until 2 neg viral cultures

28

how do you prevent HIV infection in neonate

maternal screen

29

skin eye mouth dz

HSV

30

how do you tx HSV infection

Acyclovir

31

how do you dx HSV infection

culture/PCR/LP; if seronegative mom = inc risk for baby

32

what is worse primary infection or recurrent infection of HSV

primary

33

baby w/ hx of trauma

inc likelihood of neonatal infection

34

encephalitis at day 16-17

HSV

35

what makes syphilis infection worse

co infection w/ HIV

36

how do you figure out if syphilis has been transmitted to the baby

Mother's serology (not cord serum)

37

do babys w/ congenital syphilis develop primary syphilis

No either secondary or tertiary

38

pale/thick/large placenta

syphilis

39

hydrops fetalis

syphilis

40

saddle nose, saber shins, clutton joints

syphilis

41

copper rash on hands/feet

syphilis

42

notched incisors and mulberry molars

syphilis

43

cn VIII deafness

syphilis

44

rhagades lesions

scars in skin near mouth (syphilis)

45

what causes syphilis

T pallidum

46

how do you tx syphilis

Procaine, penicillin g

47

asymptomatic @ birth and develops bone deformity, rash on hands and feet, and teeth deformities, trouble hearing

syphilis

48

how do you dx syphilis

RPR/VDRL (Ab to cardiolipin) or FTA-ABS/MHA-TP (Ab to T pallidum)

49

Wimberger's sign on xray

moth eaten appearance of bone (upper medial tibia) syphilis