Nervous System Flashcards
Cerebello/o
cerebellum
Cerebr/o
cerebrum
Dur/o
dura mater
Encephal/o
brain
Gli/o
glial cells
Lept/o
thin, slender
Mening/o Meningi/o
membranes, meninges
My/o
muscle
Myel/o
spinal cord, means bone marrow in other contexts
Neur/o
nerve
Pont/o
pons
Radicul/o
nerve root (of spinal nerves)
Thalam/o
thalamus
Thec/o
sheath (refers to the meninges)
Vag/o
vagus nerve (CN X)
Alges/o
excessive sensitivity to pain
-algesia
excessive sensitivity to pain
-algia
pain
Caus/o
burning
Comat/o
deep sleep (coma)
Esthesi/o
feeling, nervous sensation
-esthesia
feeling, nervous sensation
Kines/o Kinsesi/o
movement
-kinesia -kinesis -kinetic
movement
-lepsy
seizure
Lex/o
word, phrase
-paresis
weakness
-phasia
speech
-plegia
paralysis (loss or impairment of the ability to move parts of the body)
-praxia
action
-sthenia
strength
Syncop/o
to cut off, cut short
Tax/o
order, coordination
Afferent nerve
carries message toward the brain (sensory)
Efferent nerve
carries message away from the brain (motor)
Arachnoid membrane
middle layer of the three membranes (meninges) that surround the brain and spinal cord
Astrocyte
type of glial cell that transports water and salts from capillaries
Autonomic nervous system (ANS)
nerves that control involuntary body functions
Blood-brain barrier
protective separation between the blood and brain cells, made up of endothelial cells and astrocytes
Cerebellum
posterior part of the brain that coordinates muscle movements and maintains balance
Cerebral cortex
outer region of the cerebrum containing sheets of nerve cells; gray matter of the brain
Cerebrum
Largest part of the brain; responsible for voluntary muscular activity, vision, speech, taste, hearing, thought, and memory
Dendrite
Microscopic branching fiber of a nerve cell that is the first part to receive the nervous impulse
Dura mater
Thick, outermost layer of the meninges, surrounding and protecting the brain/spinal cord
Ependymal cell
Glial cell that lines membranes within the brain and spinal cord and helps to form CSF
Glial cell
supportive and connective nerve cell that does not carry nervous impulses; they CAN reproduce. (ex. astrocytes, ependymal cells)
Gyrus (pl. gyri)
sheet of nerve cells that produces a rounded ridge on the surface of the cerebral cortex (convolution)
Hypothalamus
portion of the brain beneath the thalamus; controls sleep, appetite, body temp, emotions, and secretions from the pituitary
Medulla oblongata
Part of the brain just above the spinal cord; controls breathing, heartbeat, and the size of blood vessels (Life center). Site of nerve fiber crossover.
Microglial cell
phagocytic glial cell that removes waste products from the CNS
Oligodendroglial cell (oligodendrocyte)
Glial cell that forms the myelin sheath covering axons
Parasympathetic nerve
Involuntary autonomic nerves that balance sympathetic stimulation; lower heart rate & bp, stimulate intestinal contractions
Parenchyma
essential, distinguishing tissue of any organ or system. Parenchyma of nervous system includes neurons & nerves
Pia mater
thin, delicate inner membrane of the meninges
Pons
part of the brain anterior to the cerebellum and between the medulla and the rest of the midbrain; a bridge connecting various parts
Sciatic nerve
nerve extending from the base of the spine through the thigh, lower leg and foot.
Spinal nerves
31 pairs of nerves arising from the spinal cord
Stroma
connective and supporting tissue of an organ, glial cells are the stromal tissue of the brain
Sympathetic nerves
stimulate body involuntarily in times of crisis; increase heart rate & bp, dilate airways, slow digestion
Thalamus
Main relay center of the brain; conducts impulses between the spinal cord and the cerebrum, control of awareness and consciousness
Vagus nerve
CN X; it’s branches reach the larynx, trachea, bronchi, lungs, aorta, esophagus & stomach.
Ventricles of the brain
Canals in the brain that contain CSF
Hydrocephalus
-abnormal accumulation of CSF in the brain, enlarged head & small face -ventriculoperitoneal shunt is placed to remove pressure on brain -can occur as an adult from infection or tumors
Spina bifida
-incomplete closure of the lumbar vertebral column during embryogenesis resulting in exposure of meninges & spinal cord -different types; occulta (posterior vertebrae have not fused, mole dimple or patch of hair over area), cystica w/ meningocele (external protruding sac containing meninges & CSF), cystica w/ myelomeningocele (external protruding sac w/ meninges, CSF & spinal cord, often associated w/ paralysis & hydrocephalus) -Spina bifida is just one type of neural tube defect (congenital anomaly of nervous system occurring during first 4 weeks of gestation), folic acid deficiency is strongly associated w/ these
Alzheimer’s disease (AD)
-chronic disorder that accounts for >50% of dementia cases, usually in persons >65yo -progressive impairment of intellectual function, may compromise language and memory, visuospatial skill, behavior and personality & cognition -unknown cause, but associated w/ plaques and neurofibrillary tangles w/ amyloid deposits -signs/symptoms; short term memory loss, loss of expression, aphasia (language comprehension difficulties), problem-solving difficulties, thought disorders, difficulties w/ ADLs, problems w/ concentration, social withdrawal
Amyotrophic lateral sclerosis (ALS/Lou Gehrig disease)
-degenerative disease which affects the upper & lower motor neurons -signs/symtoms; unexplained weight loss, focal wasting of muscle groups, limb weakness w/ variable symmetry & distribution, difficulty walking, difficulty swallowing, slurring of speech, inability to control affect, atrophy, fasciculations (small muscle twitches), hyperactive deep tension reflexes, SPARES COGNITIVE, OCULOMOTOR, SENSORY & AUTONOMIC FUNCTIONS
Epilepsy
-chronic brain disorder characterized by recurrent seizure activity; mostly idiopathic. -seizure; abnormal paroxysmal neuronal discharge of the brain, which may cause a transient disturbance of cerebral function, may be partial (limited to part of a cerebral hemisphere; simple & complex seizures) or generalized (petit mal/absence, febrile, tonic-clonic/grand mal, or status epilepticus). Complex partial is most common, followed by tonic-clonic. -Pt’s often have weakness & confusion post-seizures (postictal) -May have Todd’s paralysis, contralateral postictal paralysis & persistent weakness
Huntington disease (Huntington chorea)
-autosomal dominant disorder on chromosome 4 characterized by dementia and chorea; gradual onset & slow progress -symptoms generally appear after 30yo; chorea (abnormal, involuntary muscle movement), dysphagia, dysarthria, impaired recent memory, impaired judgement, intellectual decline, emotional disturbances, depression, anxiety, delusion, aggressiveness, urinary incontinence, bowel incontinence… -no cure & diagnosis is often after pt has reproduced
Multiple sclerosis (MS)
-inflammatory, progressive demyelination of the white matter of the brain and spinal cord resulting in multiple neurological signs and symptoms -unknown cause, pt usually
Myasthenia gravis (MG)
-autoimmune disorder of neuromuscular junction resulting in a pure motor syndrome (antibodies block Ach transmission) -males in 5th decade and females in 3rd decade -signs/symptoms; ptosis (drooping eyelids), diplopia (double vision), facial weakness, fatigue on chewing, dysphagia, dysarthria, dysphonia. neck, proximal limb, respiratory, and generalized weakness
Palsy
paralysis (partial or complete loss of motor function) -cerebral palsy; damage to cerebrum during gestation or birth -bell’s palsy; unilateral facial paralysis secondary to facial nerve (CN VII) problem (viral infection usually), complete recovery possible
Parkinson disease (parkinsonism/paralysis agitans)
-chronic, degenerative disease of basal ganglia w/ an unknown cause (possible toxin exposure). associated w/ dopamine depletion -signs/symptoms; expressionless facies (mask face), infrequent blinking, positive myerson sign (repetitive tapping over bridge of nose produces sustained blink), fine slowly spreading tremor, pill-rolling resting tremor, muscular rigidity and weakness, shuffling gait w/o arm swing, bradykinesia w/ postural instability, possible decreased intellectual function
Tourette syndrome
-Hereditary chronic neuromuscular disorder consisting of various motor/vocal tics (sudden involuntary, brief & repetitive motor movements) -Symptoms begin in childhood & location, number, frequency & complexity of tics changes over time -Signs/symptoms; tics occur many times a day & change over time (may only have one at a time). Motor tics include facial grimacing, blinking, head or neck twitching, tongue protruding, sniffing, touching. Vocal tics include grunts, snorts, throat clearing, barking & complex tics w/ echolalia (repeating words of others), palilalia (repeating one’s own words), coprolalia (use of obscenities), copraxia or copropraxia (use of obscene gestures)
Meningitis
-inflammation of membranes of the brain/spinal cord usually caused by viral (aseptic) or bacterial (more serious, pyogenic) sources but sometimes fungal -signs/symptoms; headache, fever, sensorial disturbances, neck & back stiffness, photophobia -diagnosed by CBC, blood cultures, CXR, LP (lumbar puncture). CT usually done before LP if space-occupying lesion is suspected