Neuro 1 pt6 Flashcards
(26 cards)
Diff btwn stroke and syncope – they fall down and
blood makes it to the brain with syncope.
Who most often gets Syncope?
Young people and old people
D/O of movement and posture resultant from insult to immature CNS (in utero)
Developmental delay: failure of child to reach normal milestones of gross or fine motor, language, social-adaptive skills
Cerebral Palsy
ratio of Cerebral Palsy cases with seizures, mental retardation
1/3 have seizures
60% mentally retarded
What does TIA stand for?
Transient ischemic attack/stroke
80-85% of strokes are ___, the rest are ___
most are ischemic
rest are hemorrhagic
After a stroke, there is a 10.5% risk of another stroke in following __, but the highest risk in first __!
3 months
2 days
ischemia from TIA is reversible for how long?
<24 hours
2 causes of a stroke
blockage or hemorrhage
__% cardiac output used by brain
Brain has only _ mins of glucose energy stores; - seconds of O2 stores
20%
2 minutes glucose energy
8-10 seconds of O2 in storage
Stroke- pathogenesis can come from: (3)
ABC’s
Artery, blood, cardiac reasons
Stroke pathogenesis from ABC
Artery (4)
hemodynamic signif stenosis(low flow), atherosclerosis in neck
Carotid dissection (tear of intima of vessel)
Intracranial stenosis
Stroke pathogenesis from ABC
Blood (2)
acquired and genetic prothrombotic states.
Any inflammatory state (like UTI/PNA) will produce cytokines and interleukins which will make the platelets more “sticky”
Blood reasons for a stroke: What is an lg. protein that participates directly to plt adhesion at site of vessel injury
Von Willebrand factor
5 cardiac reasons for a stroke (hint: 3 are the same thing)
a.fib
a.fib
a.fib
PFO (patent foramen ovale)
low EF%
Tests to run following a stroke: (7)
STAT head CT(N/V favor bleed)
CTA arch/neck/head (Computed Tomography Angiography)
angiography and possible clot retrieval
MRI Brain(-)/MRA neck(+)/head(-)
TTE/TEE (trans thoracic/esophogeal echocardiogram)
Carotid Doppler - vestige of workup of old
(stroke) What test is this? – inject iodine dye. See how brain takes it up, see if the brain is dying.
A / mismatch means there is some brain to save
CT Perfusion
Diffusion/Perfusion mismatch means there is some brain to save
Run which test when there is a PFO causing a stroke?
LE Dopplar
If there is a real allergy to IV dye in CT scan using IV dye, do what? (2)
Prednisone 60mg 13h, 7h & 1 hour prior to test
Benadryl 50mg 1 hour prior to test
Anterior circulation stroke vs. posterior circulation stroke depends on where it occurs in relation to:
Circle of Willis
How many branches does internal carotid have in the neck?
Zero. (Ext. carotid has branches in the neck)
*ACA (Anterior cerebral artery) infarct affects the __
*right leg paresis/plegia
Head's vascular supply: \_\_: medial 1/3 cortex superiorly (x occipital) \_\_: lateral 2/3 cortex (x occipital) \_\_: visual centers posteriorly \_\_: supplies: Basal Ganglia
ACA MCA PCA anterior, middle, posterior cerebral arteries Lenticulostriate supplies basal ganglia
MCA Infarct causes:
think R face/arm paresis/plegia