Indication:
Anticonvulsants
Generic names:
Anticonvulsants to treat seizures
Nursing considerations:
Anticonvulsants
Most common side effect:
Anticonvulsant: phenytoin
gingival hyperplasia
Nursing considerations:
phenytoin: gingival hyperplasia
Teach to floss regularly and use a soft toothbrush.
Most common adverse reaction:
Anticonvulsant: phenytoin
pancytopenia
Nursing considerations:
phenytoin: pancytopenia
(Immediate complication)
Monitor WBC and platelets - assess for bleeding and infection.
Hold med and notify HCP for active bleeding or signs of infection.
What is the therapeutic level of phenytoin?
10 - 20
Generic names:
Antiparkinsonian drug

Most common side effects:
Antiparkinsonian drug
Anticholinergic side effects (use caution if taking other anticholinergic meds):
“can’t see, can’t pee, can’t spit, can’t shit”
Indication:
neostigmine, pyridostigmine
Muscle stimulant to treat myasthenia gravis.
Mechanism of action:
neostigmine, pyridostigmine
Prevents breakdown of acetylcholine (a cholinesterase inhibitor).
This prevents muscle weakness.
Nursing considerations:
neostigmine, pyridostigmine
What are the symptoms of a cholinergic crisis (overmedicated) and myasthenic crisis (undermedicated)?
The similar symptoms make it difficult to determine quickly if the client is undermedicated or overmedicated.
What is a myasthenic crisis?
(Immediate complication)
A myasthenic crisis is when the client doesn’t get enough of their medication (undermedicated), causing muscle weakness.
It usually occurs about 3 hours after med administration.
What is a cholinergic crisis?
(Immediate complication)
A cholinergic crisis is when a client gets too much of their medicine (overmedicated), causing muscle weakness.
It usually occurs about 1 hour after med administration.
What is an edrophonium (Tensilon) test?
Used to determine if the client is in a myasthenic crisis or cholinergic crisis:
What is the antidote to a cholinergic crisis?
Atropine sulfate (an anticholinergic)
Which medication is an osmotic diuretic used to treat increased intracranial pressure?
mannitol
Nursing considerations:
mannitol
Medication is used to get extra fluid off the brain.
Generic names:
Anticonvulsants to treat nerve pain
Generic names:
Antialzheimer
donepezil, memantine
Mechanism of action:
Antialzheimer
Increases synaptic transmission.