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Flashcards in Neurotoxins Deck (3):
0

Tetrodoxin (TTX) / saxitoxin

From pufferfishes and algae,
*Bind to and block sites near the surface of Na channels

1

Batrachotoxin, aconitine, veratridine, and scorpion venom

Block Na channels by binding to their receptors OR by holding the voltage sensor (S4 segment of alpha1 subunit) at extracellular position
*Some neurotoxins also block Ca or K channels (w-conotoxins from snail and charybdotoxin from scorpions)

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Neurotoxin effects

rapid paralysis, seizure, and death