Flashcards in Non-infectious inflammatory diseases of the lung Deck (33)
multisystem granulomatous inflammatory disease of unknown etiology
what are the risk factors for sarcoidosis (ethnicities, exposures)?
exposure to insecticides, ag employment, microbial aerosols
what are the general manifestations / clinical presentation of sarcoidosis?
involvement of lymphatic and pulmonary system
dry cough, SOB
like TB without the infectious part
what is seen on PE with sarcoidosis?
skin lesions (lupus pernio, erythema nodosum)
what is seen on labs in sarcoidosis?
what ancillary tests should be performed for sarcoidosis?
ECG (for heart block)
what is seen on PFTs in sarcoidosis?
usually interstitial - limits expansion
what is the diagnostic procedure for sarcoidosis? what does it check for?
bronchoscopy to check for
BAL - lymphocyte, granulocyte count
when are systemic corticosteroids indicated for sarcoidosis?
symptomatic stage II
what are the CT diseases that affect the lung?
dermatomyositic and polymyositis
what are the demographics and clinical features of RA that affects the lung?
male > female 50-60 yo
what is the presentation for rheumatoid lung disease?
non productive cough
dyspnea on exertion
may precede joint disease by years
what are the auscultatory findings of rheumatoid lung disease?
inspiratory fine crackles
what are the radiographic findings of rheumatoid lung disease?
nodules that can cavitate
what are the medications for rheumatoid lung disease?
what lab result is indicative of rheumatoid lung disease? why?
bacteria are consuming the glucose
what are the two types of diffuse scleroderma lung disease?
interstitial lung disease
what is indicative of interstitial lung disease form of scleroderma on auscultation? what type of lung physiology is represented?
restrictive lung physiology
what is seen in the limited (CREST) form of scleroderma?
what is the most common presentation of SLE pulmonary involvement? what are other findings?
increased risk for DVT/PE** (hypercoagulable state)
what constitutes sjogren syndrome lung involvement?
bronchiestasis and bronchiolitis
what is a common manifestation of polymyositis / dermatomyositis pulmonary involvement?
aspiration pneumonia secondary to pharyngeal muscle weakness
what are the PFT findings for polymyositis / dermatomyositis?
what structures are involved?
necrotizing granulomatous vasculitis of small and medium vessels
upper and lower respiratory tract and kidneys
what are the symptoms / presentations of wegener's granulomatosis?
which antibody is specific to wegener's syndrome?
what is the diagnosis for goodpasture's syndrome?
presence of anti-glomerular base membrane antibodies
what is seen on bronchoscopy for goodpasture's syndrome?
persistent bloody fluid that does not clear on serial samples
how can diffuse alveolar hemorrhage present?
as the initial manifestation of a pulmonary vasculitis
what is the triad of churg-strauss syndrome?
what are the two phases of churg-strauss syndrome?
what is are the organ involvements in churg-strauss syndrome?
reversible airflow limitation
GI - can be severe