NP: Lecture 7 Epilepsy + Flashcards

1
Q

epilepsy=

A

continuous tendency for sudden recurring episodes of electrical discharges

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

epilepsy op 3 levels

A

electrical discharge - brain level
behavioural manifestations - behaviour level
epileptic seizures - terminology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

hoeveel mensen ooit een seizure in hun leven

A

10%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

prevalence epilepsy

A

4%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

bij wie komen seizures het vaakste voor

A

< 10 en > 65 jaar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

hoeveel epilepsy start voor 18 yr

A

50%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

seizure types based on onset

A

focal
generalised
unknown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

epilepsy types

A

focal
generalised
combined generalised and focal
unknown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

hoe gaat het vanaf seizure

A

seizure types -> epilepsy types -> epilepsy syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ethiology

A

structural
genetic
infectious
metabolic
immune
unknown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

4 dingen waarop epilepsy classifications gebaseerd zijn

A
  1. altered consciousness
  2. involuntary movements
  3. perceptual and autonomous changes
  4. behavioural changes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

2 ways you can classify epilepsy

A

A. seizure classification: focus on symptoms
B. epilepsy syndrome classification: seizure symptoms + additional clinical factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

focal/partial

A

starts in one area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

generalised

A

whole brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

vanaf focal verdeeld in

A

simple - retains awareness
complex - altered awareness and behaviour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

vanaf simple kan hij naar

A

complex, of secondary generalised

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

generalised naar…

A

Absences
Myoclonic seizures
Tonic-clonic seizures
Tonic seizures
Clonic seizures
Atonic seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

tonic =

A

sudden tension in muscles, stiffening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

clonic =

A

stiffening and relaxing of muscles alternates repeatedly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

atonic=

A

loss of muscle strength

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

myoclonic=

A

muscle twitching, jerking/spasms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

3 vragen bij focal

A

aware or impaired awareness?
motor onset or non motor onset?
progress to bilateral tonic-clonic?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

2 vragen bij generalised

A

motor (tonic-clonic or other)?
non-motor (absences)?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

unknown 2 vragen

A

motor/non motor?
unclassified? dus niet de other categories fitting of insufficient information

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
aware during seizure means
knowledge of self and environment, consciousness intact
26
B: epilepsy syndrome classifications 3 soorten hierbij
location related generalised epilepsy special
27
location related 3 soorten
ideopathic (cause is unknown) cryptogenic (strong suspicion of cause) symptomatic (cause is known)
28
generalised B criteria 3 soorten
ideopathic (cause unknown) cryptogenic (strong suspicion of cause) symptomatic (cause is known)
29
epilepsy special
-
30
welke classificatie laat de onset zien
alletwee, A en B
31
welke classificatie laat de cause zien
alleen B
32
childhood absence epilepsy =
generalized idiopathic
33
temporal lobe epilepsy=
location related symptomatic
34
bij tumoren waarschijnlijk
location related symptomatic
35
hoe heet epilepsy voor flitsen
photosensitive epilepsy
36
prevalence photosensitive epilepsy
3% of people with epilepsy, dus heel weinig eigenlijk
37
who is affected by photosensitive epilepsy
mainly children and teens with generalized epilepsy
38
vb van generalised epilepsy bij teens
juvenile myoclonic epilepsy, can be triggered by a lack of sleep
39
Epilepsy is also a classification in DSM-5, ICD-10: Very detailed scoring
oke
40
3 motor symptoms of epilepsy
o Tonic: Muscle contractions and body movements o Clonic: Semi-rhytmic muscle movements o Myclonic spasms: Very short muscle contractions (limbs)
41
autonomic effects of epilepsy
seating, flushing
42
visual effects of epilepsy
flashes, blurring, scotomas
43
auditory effects
ringing, hissing
44
somatosensory effects
tingling
45
pre-ictal and post-ictal
time before onset of seizure and time after seizure
46
pre-ictal hoe lang
several hours to days
47
post-ictal hoe lang
several minutes to hours (sometimes days)
48
dus welke periode is korter
post-ictal is meestal korter, pre-ictal kan lang duren
49
wat zie je bij pre-ictal vaak
behavioural restlessness or other changes in behaviour
50
post-ictal symptoms
restlessness increased appetite/thirst disorientation agression
51
door epilepsy increased risk of...
psychological, psychiatric and cognitive impairments
52
mowrers two factor model
Mowrer’s theory of conditioning according to which (1) fear is attached to a neutral stimulus by pairing it with a noxious unconditioned stimulus, and (2) a person learns to avoid the conditioned stimulus and so extinction of the conditioning is prevented.
53
mowrer critiques
many people with anxiety cannot remember exposure to threatening event. many people with threats do not develop anxiety
54
but explanations for mowers critique
does not have to be direct can also develop via modeling can develop via verbal instruction (mom afraid of spiders)
55
risk of impairments is determined by 3 clinical factors...
1. stable -> brain anomaly, age of onset, seizure type 2. dynamic -> frequency, timespan, duration of dyscharges 3. treatment -> drugs, neurosurgery
56
biopsychosocial mdoel of epilepsy
* Biological: stable/dynamic/treatment factors & it’s cognitive consequences. * Psychological: how one deals with having epilepsy and it’s consequences. * Social: how one’s environment deals with the person with epilepsy.
57
over welke vorm van epilepsy weten we meer
we weten meer over symptomatic than idiopathic (duh)
58
5 symptomen bij beiden idiopathic en symptomatic
attention information processing speed psychomotor visuo-spatial skills executive dysfunctions
59
symptomatic symptoms
location is belangrijk: temporal = memory frontal = executive functions parietal/occipital = no specifics
60
psychological consequences of epilepsy
depression anxiety low self esteem psychoses lack of social support stigma
61
voor heoveel procent is drugs genoeg
70%-75%
62
hoeveel van die mensen hebben poly drugs
5-10%
63
hoeveel hebben monodrugs
65%
64
hoeveel is drug resistant
20-30%
65
option voor drug resistance?
surgery
66
hoeveel mensen seizure free na surgery
70%
67
hoeveel mensen seizure reductions na surgery
30%
68
dus hoeveel mensen hebben er iets minder last van
iedereen (60% vrij van seizures, 30% seizure reductions)
69
antiepileptic drugs effects psy
Cognitive side effects are hard to determine, but always CHECK what is prescribed can Impact Quality of Life
70
tonic clonic details
These used to be known as “grand mal” seizures and are the ones generally portrayed in the movies. These involve convulsions and are very noticeable. The muscles stiffen, including vocal chords which may cause the person to cry out or groan. A person may lose bladder or bowel control during a Tonic Clonic seizure. A person can also get hurt from falling when having a Tonic Clonic seizure.
71
complex focal seizures
These types of seizures can start with an aura which might allow time to get to a safe place. The person having a Complex Partial Seizure is not aware of their surroundings and can stare into space, repeatedly tug at their clothing or smack their lips. If they are standing when a seizure hits, it is possible they will lose their balance and fall leading to a possible injury
72
simple focal seizures
These can include motor seizures or sensory seizures. The sensory seizures are particularly difficult for the person with epilepsy if people (including medical professionals) are not educated about seizures. Sensory seizures can include hallucinations and a feeling of dizziness or spinning which can be extremely uncomfortable
73
absence seizures
Absence seizures can last only a few seconds and may go unnoticed. Sometimes it will seem as if the person is not paying attention or is staring into space. It is very common for parents or teachers who are not familiar with seizures to assume a child having absence seizures is deliberately not paying attention. This is not the case. Complex Absence Seizures can include various movements such as blinking or chewing.
74
myoclonic seizures
These seizures are characterized as brief, jerks of movement or twitching. Sometimes there are several at once but generally there is only one that lasts a second or two.