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Flashcards in Oncology (MR) Deck (33):
1

Differentials for enlarged LN?

Infection Neoplasia Inflammatory Immune Mediated

2

Ruleouts for Infection of LN?

Tooth Abscess Salivary Gland Erlichia Rocky Mtn Spotted Fever Lymes Fungal

3

Pros and Cons of FNA (cytology)?

Cheap, Quick, Easy. Often gives dx Individual cells Cons: lack of tissue architecture Not always diagnostic sample Hemodilution and inflammation make it hard to decipher

4

What Neoplasia enlarge 1 ln?

mast cell tumor of head/neck melanoma Lymphoma Metastatic cancer

5

What is the most common oral tumor in dogs?

Melanoma

6

With Cytology what is the 1st question to ask yourself? 2nd ?:

Is this a diagnostic sample Cell type What are cell types (3 main)? Round Epithelial Mesenchymal

7

Mesenchymal cells nucleas?

Round or ovid

8

Cytoplasm of Mesenchymal cells?

Spindle w/

9

Diagnostics for Enlarged LN?

FNA Min Database

10

Differentials for enlarged LN?

Infection Neoplasia Inflammatory Immune Mediated

11

Ruleouts for Infection of LN?

Tooth Abscess Salivary Gland Erlichia Rocky Mtn Spotted Fever Lymes Fungal

12

Pros and Cons of FNA (cytology)?

Pros: Cheap, Quick, Easy. Often gives dx Individual cells Cons: lack of tissue architecture Not always diagnostic sample Hemodilution and inflammation make it hard to decipher

13

What Neoplasia enlarge 1 ln?

mast cell tumor of head/neck melanoma Lymphoma Metastatic cancer

14

What is the most common oral tumor in dogs?

Melanoma

15

With Cytology what is the 1st question to ask yourself? 2nd ?:

Is this a diagnostic sample Cell type What are cell types (3 main)? Round Epithelial Mesenchymal

16

Mesenchymal cells: Nucleus? Cytoplasm? Exfoliation?

Nucleus: round to ovoid Cytoplasm: spindle or fusiform, often have wispy tails Cells exfoliate individually Occasional clumps Samples are often poorly cellular

17

Mesenchymal Cancer type: _________________?

Sarcoma

18

Epithelial Cells: Nucleus? Cytoplasm? Exfoliate?

Nucleus: round ? Cytoplasm: round, ovoid, or angular, distinct and intact cytoplasmic borders Exfoliate well, in sheets or clumps

19

Epithelial Cells: Cancer type: _______________?

Carcinoma

20

Difficulty with epithelial cell samples?

Bacteria cannot make dx until understand presence of bacteria

21

Round cells: Nucleus Cytoplasm? Exfoliate?

Nucleus: round Cytoplasm: round, scant to moderate amount . Exfoliate well, and individually (discrete)

22

Round cell Cancer types?

Lymphoma Transmissible venereal tumor Plasmacytoma Histiocytoma Mast cell tumor

23

What is the Great Cytologic Pretender?

Melanoma Amelanotic melanoma - look like other cancers. Need histopath

24

Criteria of malignancy?

High or variable: Anisokaryosis Anisocytosis Chromatin clumping Nuclear molding Multinucleation Abnormal mitotic figures or increased numbers of mitotic figures

25

When do you want Histopathology?

-Tissue articture -background inflammation - cant get sample on cytology

26

Histopath is very Dependent on?

sample quality and quantity

27

2 Types of histopath for smapling? How do you choose?

Pretreatment biopsy Excisional biopsy How big is it? Will total removal be therapeutic?

28

Your first chance to cut is your chance to?

Cure

29

Why would you Ink for margins?

Tells pathologist where margins are so they know if tumor incision is complete = did you get it all?

30

Immunohistochemistry: looks for cell markers. Great for dx of?

Melanoma

31

When is a pre-treatment biopsy recommended?

Type of treatment altered; Extent of surgery altered Difficult area to reconstruct/ obtain complete margins Knowledge of tumor type & prognosis

32

When is pretreatment biopsy not indicated?

Treatment or extent of surgery not changed (splenic mass, testicular mass) Surgical procedure for biopsy as risky as surgery (spinal cord tumor)

33

What should you suspect in a dog that is acutely vomiting?

Aspiration