Ordinary Connective tissue Flashcards

(55 cards)

1
Q

What is all CT made up of?

A

Cells,fibres and ground substance

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2
Q

What are the 5 functions of CT?

A

Extracellular matrix that connects and binds organs and cells within the body
Gives support to the body
Facilitates cellular defence mechanisms
Repair
Provides an avenue for communication and transportation

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3
Q

How is CT supplied?

A

By blood and lymphatic vessels and nerves

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4
Q

What are the two types of CT?

A

Ordinary and special

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5
Q

What are the three types of ordinary CT?

A

Loose, areolar
Dense irregular
Dense regular

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6
Q

What are the 6 special CT?

A
Adipose tissue
Cartilage 
Bone
Dentin
Haematopoeitic tissue
Endothelium
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7
Q

What makes up the extra cellular matrix?

A

Fibres and ground substance

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8
Q

What type of cells are present in CT?

A

Fixed and wanderig

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9
Q

What type of fibres are present in CT?

A

Collagen
Reticular
Elastic

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10
Q

What is the ground substance of CT?

A

Highly hydrated gel
Glycosaminoglycans
proteoglycans
glycoproteins

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11
Q

What type of cell is a fibroblast and what is its functions?

A

fixed

ECM production

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12
Q

What type of cell is a mesenchymal and what is its functions?

A

fixed

CT precursor

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13
Q

What type of cell is a reticular cell and what is its functions?

A

fixed

production of reticular fibres

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14
Q

What type of cell is an adipocyte and what is its functions?

A

fixed

fat storage

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15
Q

What type of cell is a macrophage and what is its functions?

A

wandering

phagocytosis

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16
Q

What type of cell is a plasma cell and what is its functions?

A

wandering

antibody production

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17
Q

What type of cell is a mast cell and what is its functions?

A

Chemical mediators

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18
Q

What type of cell is a white blood cell and what is its functions?

A

wandering

defence

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19
Q

What is the principle cell of ordinary CT?

A

Fibroblast

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20
Q

What are fibrocytes?

A

Quiescent fibroblasts (resting)

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21
Q

What is the role of collagen?

A

Tough
Provides high tensile strength
Stretch resistant
most abundnat protein (25%)

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22
Q

What is the role of elastic?

A

Long thin fibres

allow for stretch and recoil

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23
Q

What is reticular fibres made from?

A

Type III collagen

24
Q

What is the role of reticular fibre?

A

Branched, thin collagenous fibres

Form and extensive delicate networks

25
What is the role of Type I collagen?
Provides tensile strength, 90% of total collagen, dermis, ligaments, tendons, bone, dentin
26
What is the role of Type II collagen?
Found in hyaline and elastic cartilage
27
What is the role of Type III collagen?
Reticulin
28
What is the role of Type IV collagen?
Found in the basal lamina works with type VII
29
What is the role of Type VII collagen?
Forms anchoring fibrils works with IV
30
What is procollagen?
three individual collagen molecules combine within a cell
31
How is tropocollagen formed?
Procollagen is secreted from the cell and proteolytic enzymes cleave propeptides
32
What are tropocollagen molecules used for?
align to linear arrays to produce collagen fibrils
33
What are collagen fibrils for?
Assemble to form a collagen fibre - covalent cross-linking occurs
34
What is a collagen bundle?
Collagen fibres cominh together to form a a pink wavy structure (collagen bundles)
35
What is the main component of elastic fibres?
Elastin
36
What is the elastin core made up of?
Fibrils made up of the glyco protein fribrillin
37
What is the role of the ground substance?
Resists compressive forces on the matrix - provides mechanical strength Functions as a molecular sieve through which nutrients, metabolites and hormones diffuse between blood capillaries and cells
38
What are glyosaminoglycans (GAG)?
Unbranched polysaccharide chains composed of repeating disaccharide units
39
What is the role of GAGs?
Maintains tissue architecture - rigidity and turgor provides structural integrity to cells and provides passageways between cells allowing for cell migration.
40
What is a proteoglycan molecule?
A GAG bound to a protein core
41
Give 4 examples of GAGs
Hyaluronic acid- wound healing Keratan sulphate- bone and cartilage and cornea Chondroitin sulphate- bone and cartilage and heart valves Heparin Sulphate - basal lamina
42
What does areolar mean?
Open space
43
What is the role of dense irregular CT?
Adapted to offer resistance & protection withstands tensions in different directions Predominance of collagen fibres which run haphazardly
44
What is the role of dense regular CT?
Offer resistance in one direction or plane Provide maximum tensile strength Predominant collagen aligned to stress resist
45
What is the role of loose areolar CT?
holds structures in place | provides a packing framework for organ suppport
46
Whats is loose areolar CT made up of?
Collagen and fibroblasts abundance of ground substance
47
Where is loose areolar CT located?
below epithelia forms the lamina propria of a mucosa surrounds capillaries
48
What is dense irreagular CT made up of ?
collagen fibres densely packed and irregularly arranged | smaller proportion of Ground substance
49
Where is Dense irregular CT located?
Dermis Submucosa of digestive tract Periosteum & perichondrium Fibrous capsules of organs
50
Where is Dense regular CT located?
Ligaments (Bone to bone) Tendons (bone to muscle) Aponeuroses
51
What adipose tissue composed of?
Adipocytes
52
What are adipocytes?
Fat cells - individual lipid droplet surrounded by thin layer of cytoplasm and nucleus
53
What is the function of adipose tissue?
Energy store, cushions, insulation | Metabolism or brown fat produces heat in the newborn
54
Where is adipose tissue found?
Under skin around kidneys within the abdomen breasts
55
Where is the origin of CT?
Mesoderm