Path Bleeding disorders Flashcards
overproduction of corticosteroids from adrenalcortex
Cushing’s Syndrome brittle blood vessels, severe osteoporosis, obesity, diabetes,high BP
o Prolonged steroid medication use can have symptoms similar to
Cushing’s, easy bruising
bruises > 2 cm
Ecchymoses
– larger than a pinpoint, but
Purpura
– leak of blood into cavities o
Hematoma
Rupture of middle meningeal artery
epidural hematoma
Thrombocytopenia
Normal amount of platelets in blood: 250,000 – 300,000
no platelet activation cannot form platelet plughemorrhagic gastroduodenitis— balck stool
Von Willebrand’s Disease
– increased amount of blood lost during menstruation
menorrhagia (related to von willebrand’s)
seriousdisorder manifested usually from uterus cancer, which results inloss of blood between menstruation periods
metrorrhagia/not related to Von W
non-production of certain protein clotting factors
Hemophilia
Hemophilia genetics
mother to son X chromosome (skips a generation)
nonproduction of CF 8 viii
Hemophilia A
nonproduction of CF 9
Christmas disease/Hemophilia B
Hemoarthritis
Trauma leads to blood in joint spaces, esp. Knee jointIron released from heme into blood destroys the joint cartilage