Pathologic RBC Forms Flashcards Preview

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Flashcards in Pathologic RBC Forms Deck (10):
1

Acanthocyte = spur cell

SPINE-Y
Liver disease
A-beta-lipoproteinemia

2

Basophilic stippling

Lead poisoning
Siderblastic anemia
MDS

3

Dacrocyte / teardrop cell

Squeezed out of the bone marrow
Think bone marrow infiltrate aka myelofibrosis

4

Degmacyte = bite cell

G6PD def

5

Echinocyte = burr cell

Spiney but projections are more uniform across the entire RBC membrane and smaller
ESRD
Liver disease
Pyruvate kinase def

6

Elliptocyte

Rod shaped RBC
Hereditary elliptocytosis - mutation in genes coding RBC membrane

7

Ringed sideroblast

Excess iron in mitochondria - sideroblastic anemia

8

Target cell

HALT the target
HbC disease
Asplenia
Liver disease
Thalassemia

9

Heinz bodies

G6PD def
Oxidize HB-SH groups -> Hb precipitates -> damage RBC -> bite cells

10

Howell Jolly bodies

Dysfxnal spleen
Basophilic nuclear remnants in RBCs that should have been taken out in the spleen