Peripheral Nervous System (Exam 3) Flashcards Preview

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Flashcards in Peripheral Nervous System (Exam 3) Deck (51):
0

The efferent division is divided into two parts

Somatic
Autonomic

1

Affectors

Somatic- skeletal muscle
Autonomic- smooth and cardiac muscle, glands, viscera

2

Pathway

Somatic- single neuron
Autonomic- 2 neuron chain with a synapse in between

3

Neurotransmitters

Somatic- Ach
Autonomic- Ach, epinephrine, neuroepinephrine

4

Neurotransmitter effect on target cell

Somatic- always excitatory
Autonomic- excitatory or inhibitory

5

Cholinergic fibersq

Fibers that release Ach

6

Adrenerhic fibers

Neurons that release epinephrine and neuroepinephrine

7

Cholinergic receptors

Bind and respond to Ach

Nicotinic 1&2
Muscarinic 1,2,&3

8

Adrenergic receptors

Binds and respond to epinephrine and neuroepinephrine

Alpha 1&2
Beta 1&2

9

Preganglionic fibers

Neuron whose cell body lies in the CNS
Releases NT that across a Neuro-neuronal synapse and binds with a second neuron

10

Postganglionic fiber

Neuron whose cell body lies in the PNS
Binds to the NT released from the postganglionic fiber
Axon extends to the effector organ
Releases NT that bind to the effector organ

11

Autonomic NS is divided into two parts

Parasympathetic and sympathetic

12

Dual innervation

Most viscera is innervated by both the parasympathetic and the sympathetic NS

13

Autonomic tone

One division is exhibiting more tone depending on what the body needs

14

Parasympathetic and sympathetic ______ each other and _______ are active all the time

Oppose
Both

15

Function of the parasympathetic NS

Rest and digest
Vegetative and Maintance activities
Conservation of ATP

Ex. Decrease HR, decrease BP, increase digestive function

16

Function of the sympathetic NS

Fight or flight
Prepares body to deal with an energetic situation
Uses ATP

Ex. Increase HR, increase BP, decrease digestive function

17

Origin sites of preganglionic fibers

Sympathetic- thoracolumbar region of the spinal cord (T1-L2)
Parasympathetic- cranial and spinal nerves

18

Occulomotor (3)

Smooth muscle of the eye that influences pupil size and eyeball movement

19

Facial (7)

Nasal glands
Lacrimal glands
Submandibular and sublingual salivary glands

20

Glassopharyngeal (9)

Parotid salivary gland

21

Vagus (10)

90% of the parasympathetic supply
Branches into the
Cardiac plexus
Pulmonary plexus
Esophageal plexus
Descending aortic plexus

22

Cardiac plexus

Innervates the heart

23

Pulmonary plexus

Innervates the lungs and bronchi

24

Esophageal plexus

Innervates the esophagus

25

Descending aortic plexus

Innervates most abdominal viscera

26

Sacral region of the spinal cord Innervates:

Distal half of the large intestine
Urinary bladder
Reproductive organs

27

Location of ganglia (origin of postganglionic fiber)

Sympathetic- sympathetic ganglionchain
Collateral ganglion
Adrenal medulla
Parasympathetic- terminal ganglion

28

Sympathetic ganglionchainq

Close to the spinal cord

29

Collateral ganglion

Midway between the spinal cord and the effector organ

30

Adrenal medulla

Internal portion of the adrenal gland

31

Some preganglionic fibers synapse

With the adrenal medulla

32

Preganglionic sympathetic fiber releases Ach which binds to N1 receptors on medullary tissue

This causes a release of epinephrine and neuroepinephrine into the blood stream
(system wide sympathetic response)

33

Terminal ganglion

Close to the effector organ

34

Nicotinic receptor

Receptor stimulation by Ach is always excitatory
N1
N2

35

N2

On sarcolemma of skeletal tissue (depolarization)

36

N1

On all postganglionic cell bodies (at all ganglia in ANS)
On adrenal medulla

37

Muscatinic receptors

Receptor stimulation by ch can result in an excitatory or inhibitory response depending on the receptor and the target organ
M1
M2
M3

38

M1

Located on neural tissue
Excitatory

39

M2

Located on heart
Inhibitory (decrease muscle contraction)

40

M3

Located on smooth muscle and glands
Excitatory

41

Alpha

Stimulation is generally excitatory
Except alpha2 on gut muscle

Alpha1
Alpha2

42

Beta

Stimulation is generally inhibitory
Except beta1 on the heart

Beta1
Beta2

43

Eye

P- pupil constriction via contraction of the circular muscle of the iris (M3)
S- pupil dilation via the contraction of the radial muscle of the iris (Alpha1)

44

Digestive glands

P- increase in secretory activity (M3)
S- decrease in secretory activity (Beta2)

45

Digestive tract smooth muscle

P- increase in motility (M3)
S- decrease in motility (Alpha2, Beta2)
Increase contraction of sphinctors (Alpha1)

46

Sphinctor

Cuff of smooth muscle between one organ and the next

47

Heart

P- decrease in HR (M2)
S- increase in HR (Beta1)

48

Liver

P- no innervation
S- glycogen breakdown (Beta2)

49

Blood vessel smooth muscle

P- no innervation
BV serving the external genetalia (M3)
S- blood vessel vaso-constriction (Alpha1)

50

Respiratory system

P- contraction of smooth muscle surrounding the bronchioles (M3)
S- relaxation of the smooth muscle surrounding the bronchioles (Beta2)

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