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Flashcards in Pharm lll Deck (25)
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1

Tetracyclines 2

doxycylcine
minocycline
broad spectrum
watch your bones/teeth, photosensitivity, prolongs QT
CI in children < 8 yo

2

Isoniazid, Nydrazid

mycolic acid synthesis inhibitor
TB -polypharm (rifampin, pyrazinamide, isoniazid)

3

TRIPLE ANTIBIOTIC

murine monomer synth inhibitor
neomycin, polymyxin B, Bacitracin

TOPICAL

4

Cephalexin, Cefdinir
others (Ceftriaxone, Cefuroxime)

cephalosporin
1st, 3rd gen
Cephalexin: UTI, skin & soft tissue infxn (cellulitis)
Cefdinir: resistant to many B-lactamases

5

Cell wall synthesis inhibitors types

1. penicillins
2. cephalosporins
3. glycopeptides

6

Penicillin V

more narrow spectrum than others - ORAL only; broken down by beta-lactamases

7

Broad spectrum penicillin for both gram pos and neg

ampicillin, amoxacillin, amoxicillin/clavulanate
INDIC: uncomplicated ENT infxn, h pylori

8

Rifaximin Vs Rifampin

Rifax - monoxycarbolic acid agent / RNA inhibit
Rifamp - anti TB

9

antibacterial glycopeptide

Vancomycin

10

Macrolides all have what in their name?

ithro
ythro
(azithro, clarithro, erythro)

11

Salmterol
ADR

LABA
prolongs QT

12

Allegra generic

Fexofenadine

13

Zyrtec generic

Cetirizine

14

Claritin generic

loratidine

15

1st gen anti-histamines are... 3

anti-cholinergics
diphenhydramine
hydroxyzine
promethazine
- can be used for serotonin syndrome

16

2nd gen anti-histamines
SE

loratadine
cetirizine
fexofenadine
SE: prolong QT
inhibits cyp 450

17

Benzonatate

cough suppressant
related to procaine

18

dextromethorphan
codeine
hydrocodone

opioid anti-tussives
cough

19

Sumatriptan MOA

5-HT1 agonist
migraine

20

varenicline

aka chantix
stop smoking
partial nicotine agonist
BB warning -mental health

21

zolpidem

zzzz- for sleep
ambien
interacts w GABA-BZ -receptors

22

2 SNRI's

duloxetine, venlafaxine
(cymbalta, effexor)
MDD
dulox is also used for GAD, diabetic peripheral neuropathy, chronic MSK pain

23

Trazodone

SARI, serotonin antag and reuptake inhibitor
MDD, insomnia (off label)

24

Mirtazapine

aka remeron, Tetracyclic
MDD
MOA unknwn

25

Amitriptyline

tricyclic antidepressant
aka elavil
MOA unknown
indic Depression