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Low Yield Semmelweis > Pharma List B > Flashcards

Pharma List B Flashcards

(59 cards)

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1
Q

Which drug must be administrated with halothen

A

Atropine

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2
Q

Which drug can cause hernia among the iv anesthetics

A

Ketamine increasing ICP

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3
Q

Which opioids is used by gynecologist

A

Nalbupin - does not relax uterus

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4
Q

Which drug increases frequency of opening CL Channel

A

Benzodiazepines

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5
Q

Competitive antg of benzodiazepines

A

Flumazenil

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6
Q

Overs agonist of benzodiazepines

A

Beta carbolines

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7
Q

Hypnotic MOA of benzodiazepines

A

Bz2 receptor . Increase nREM decrease R.E.M. And nREM 3,4

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8
Q

Which benzodiazepines don’t have active metabolites

A

Oxazapam , temazapam , lorazepam

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9
Q

Which benzodiazepines used for absence seizure

A

Clonazepam

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10
Q

Temazapem indication

A

Useful in pt having difficulty to maintain sleep .

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11
Q

For panic attacks , Which benzodiazepines will u use

A

Alprazolam and clonazapam

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12
Q

How much of phenobarbital can cause narcosis

A

1g

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13
Q

Ultra short acting barbiturates

A

Thiopental methohexital

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14
Q

Which drugs bind BDZ1 receptor

A

Eszopiclone zolpidem zaleplone . Do not alter sleep stages .

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15
Q

Which drugs are given to pregnant woman with epilepsy

A

Barbiturates

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16
Q

Indication of zaleplon

A

Induction of sleep

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17
Q

Indication of ramelton

A

Sleep onset

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18
Q

Busiprone MOA

A

Pure anxiolytics by PA of 5HT1A . Indicated in generalized anxiety ( takes 3 weeks to function )

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19
Q

Disulfiram indication

A

Alcohol withdrawal by inhibiting acetaldehyde DH .

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20
Q

Partial d2 d3 antg

A

Cariprazine - also PA to 5HT1A

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21
Q

Pa d2 antagonist 5ht2a

A

Ariprazole

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22
Q

Which drug will u use enuresis

A

Imipramine by decreasing phase 4 of slow wave

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23
Q

Which antidepressant drug is also antipsychotic

A

Amoxapine - its metabolite

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24
Q

Unicyclic anti depressant

25
Describe seratonin syndrome
Hypertension tachycardia hyperreflexia tremor delirium
26
SSRI with longest DOA
Fluoxetine
27
Vilazodon MOA
Seratonin 1alpha partial agonist . Strong anxiolytic . Taken once a day .
28
Lowest protein binding among anti depressants.
Velnafaxin
29
Which serotonin receptor exhibits anxiolytic effect when blocked
5HT2c
30
Which drug treats depression due to alcohol withdrawal
Tianeptin ( effects CRH axis )
31
Drug from antidepressants indicated for ADHD
Atomexetin
32
MOA of lithium
Increase Gi decrease Gs , similar to na thus enters cells and depolarizes them , decrease PIP2
33
Toxic plasma level of lithium
1.5-1.7 mol/ liter
34
Which diuretics help excretion of lithium
Amiloride
35
Mood stabilizers
Lithium , carbamazepine , valproate , lamotrogine
36
Anticonvulsants drug in pregnancy
Gabapentin
37
SE of phenytoin
Hirsutism , gingival hyperplasia, osteomalacia, cardiac arrythmogenic, strong enzyme inducer ( don't use oral contraceptives)
38
MOA of Gabapntin
Inhibit n type Ca channel --- decrease glutamate
39
Indications of gabapentin
Mood stabilizer, neuropathic pain , central muscle relaxant , seizure
40
MOA of vigabetrin
Irreversible inhibitor of gaba aminotransferse
41
Which anti epileptic is working on AMPA
Topiramate , lemotragine
42
Which diazepam used for absence seizures
Clonazapam
43
Drugs for absence seizures
Ethusoximide , trimethadion ( old version ) , clonazapam , valproic acid
44
Promadone MOA
Metabolites PEMA and barbiturates block Na channel and potentiate Gaba
45
Levatiracetam MOA
Modifies gaba and glutamate release | SE : aggressive behavior
46
Why ergot derivatives are less used in Parkinson's
Massive dyskinesia .
47
Amantadine MOA
Blocks muscarinic receptors and enhances dopamin . Also inhibits adenosine A2 --- disinhibition of D2 mediated effects
48
When to use anticholinergic drugs in Parkinson
In tremor dominant and drug induced Parkinson
49
Which antipsychotic is given in Parkinson
Clozapine
50
Who is the only local anesthetics that does not need vasoconstrictor
Cocain - sympathomimetic
51
Fastest acting local anesthetics
Articain ?
52
Which anti histamine eliminated from kidney unchanged
Cetirizine ,acrivastin
53
Which drug combo with anti histamine can cause severe arrhythmias
Itraconaxol ketoconazol microlids
54
What is the dose for antithrombosis effect of aspirin
75-100 mg
55
Non acidic NSAIDS
Nebumatone
56
Which NSAIDS is sulfa drug
Celecoxib
57
Cincalcet MOA
Activate ca sensing receptor and inhibit PTH
58
Name estrogen receptor antg
Fluvestrant
59
17 alpha hydroxilase inhibitors
Abirateon

Low Yield Semmelweis (37 decks)

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