pharmacology: side effects Flashcards Preview

Abbey pharm shelf/step > pharmacology: side effects > Flashcards

Flashcards in pharmacology: side effects Deck (51):
1

coronary vasospasm

cocaine, sumatriptan, ergot alkaloids

2

cutaneous flushing

vancomycin, adenosine, nicacin, Ca channel blockers, echinocandina

3

dilated cardiomyopathy

anthracyclines (doxorubicin, daunorubicin)

4

torsades de pointes

antiarrhthmics (IA, III), antibiotics (macrolides), antipsychotics (haloperidol), antidepressants (TCAs), antiemetics (ondansetron)

5

adrenocortical insufficiency

HPA suppression secondary to glucocorticoid withdrawal

6

hot flashes

tamoxifen and clomiphene

7

hyperglycemia

tacrolimus, protease inhibitors, niacin, HCTZ, corticosteroids

8

hypothyroidism

lithium, amiodarone, sulfonamides

9

gynecomastia

spironolactone, digoxin, estrogens, cimetidine, chronic alcohol, ketoconazole, marijuana

10

acute cholestatic hepatitis, jaundice

erythromycin

11

diarrhea

acamprosate, acarbose, cholinesterase inhibitors, colchicine, erythromycin, ezetimibe, metformin, misoprostol, orlistat, pramlintide, quinidine, SSRIs

12

focal to massive hepatic necrosis

halothane, amanita phalloides (death cap mushroom), valproic acid, acetaminophen

13

hepatitis

rifampin, isoniazid, pyrazinamide, statins, fibrates

14

pancreatitis

didanosine, corticosteroids, alcohol, valproic acid, azathioprine, diuretics (furosemide, HCTZ)

15

pill-induced esophagitis

tetracyclines, bisphosphonates, potassium chloride

16

pseudomembranous colitis

clindamycin, ampicillin, cephalosporins

17

agranulocytosis

clozapine, carbamazepine, propylthiouracil, methimazole, colchicine, ganciclovir

18

aplastic anemia

carbamazepine, methimazole, NSAIDs, benzene, chloramphenicol propylthiouracil

19

direct coombs-positive hemolytic anemia

methyldopa, penicillin

20

gray baby syndrome

chloramphenicol

21

hemolysis in G6PD deficiency

isoniazid, sulfonamides, depsone, primaquine, aspirin, ibuprofen,, nitrofurantoin

22

megaloblastic anemia

phenytoin, methotrexate, sulfa drugs

23

thrombocytopenia

heparin

24

thrombotic complications

OCPs, hormone replacement therapy

25

fat redistribution

protease inhibitors, glucocorticoids

26

gingival hyperplasia

phenytoin, Ca channel blockers, cyclosporine

27

hyperuricemia (gout)

pyrazinamide, thiazides, furosemide, niacin, cyclosporine

28

myopathy

fibrates, niacin, colchicine, hydroxycholoroquine, interferon-alpha, penicillamine, statins, glucocorticoids

29

osteoporosis

corticosteroids, heparin

30

photosensitivity

sulfonamides, amiodarone, tetracyclines, 5-FU

31

rash (SJS)

anti-eplileptics (esp lamotrigine), allopurinol, sulfa drugs, penicillin

32

SLE-like syndrome

sulfa drugs, hydralazine, isoniazid, procainamide, phenytoin, etanercept

33

teeth discoloration

tetracyclines

34

tendonitis/cartilage damage

fluoroquinolones

35

cinchonism

quinidine, quinine

36

parkinson-like syndrome

antipsychotics, reserpine, metoclopramide

37

seizures

isoniazid (vit B6 deficiency) cupropion, imipenem/cilastatin, tramadol, enflurane

38

tardive dyskinesia

antipsychotics, metoclopramide

39

diabetes insipidus

lithiu, demeclocycline

40

fanconi syndrome

tenofovir, ifosfamide

41

hemorrhage cystitis

cyclophosphamide, ifosfamide

42

internstitial nephritis

methicillin, NSAIDs, furosemide

43

SIADH

carbamazepine, cyclophosphamide, SSRIs

44

dry cough

ACE inhibitors

45

pulmonary fibrosis

methotrexate, nitrofurantoin, carmustine, bleomycin, busulfan, amiodarone

46

antimuscarinic

atropine, TCAs, H1 blockers, antipsychotics

47

disulfiram-like reaction

metronidazole, certain cephalosporins, griseofulvin, procarbazine, 1st generation sulfonureas

48

nephrotoxicity/ototoxicity

aminoglycosides, vancomycin, loop diuretics, cisplatin

49

cytochrome P-450 inducers

Guinness, Corona, and PBRS induce chronic alcoholism
Griseofulvin
Carbamazepine
Phenytoin
B
Rifampin
St John's wort

50

cytochrome P-450 substrates

anti-epileptics, theophylline, warfarin, OCPs

51

cytochrome P-450 inhibitors

AAA RACKS In GQ Magazine
Acute Alcohol Abuse
Ritonavira
Amiodarone
Cimetidine/ciprofloxacin
Ketoconazole
Sulfonamide
Isoniazid
Grapefruit juice
Quinidine
Macrolides (except azithromycin)