pharmacology: side effects Flashcards Preview

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Flashcards in pharmacology: side effects Deck (51)
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1

coronary vasospasm

cocaine, sumatriptan, ergot alkaloids

2

cutaneous flushing

vancomycin, adenosine, nicacin, Ca channel blockers, echinocandina

3

dilated cardiomyopathy

anthracyclines (doxorubicin, daunorubicin)

4

torsades de pointes

antiarrhthmics (IA, III), antibiotics (macrolides), antipsychotics (haloperidol), antidepressants (TCAs), antiemetics (ondansetron)

5

adrenocortical insufficiency

HPA suppression secondary to glucocorticoid withdrawal

6

hot flashes

tamoxifen and clomiphene

7

hyperglycemia

tacrolimus, protease inhibitors, niacin, HCTZ, corticosteroids

8

hypothyroidism

lithium, amiodarone, sulfonamides

9

gynecomastia

spironolactone, digoxin, estrogens, cimetidine, chronic alcohol, ketoconazole, marijuana

10

acute cholestatic hepatitis, jaundice

erythromycin

11

diarrhea

acamprosate, acarbose, cholinesterase inhibitors, colchicine, erythromycin, ezetimibe, metformin, misoprostol, orlistat, pramlintide, quinidine, SSRIs

12

focal to massive hepatic necrosis

halothane, amanita phalloides (death cap mushroom), valproic acid, acetaminophen

13

hepatitis

rifampin, isoniazid, pyrazinamide, statins, fibrates

14

pancreatitis

didanosine, corticosteroids, alcohol, valproic acid, azathioprine, diuretics (furosemide, HCTZ)

15

pill-induced esophagitis

tetracyclines, bisphosphonates, potassium chloride

16

pseudomembranous colitis

clindamycin, ampicillin, cephalosporins

17

agranulocytosis

clozapine, carbamazepine, propylthiouracil, methimazole, colchicine, ganciclovir

18

aplastic anemia

carbamazepine, methimazole, NSAIDs, benzene, chloramphenicol propylthiouracil

19

direct coombs-positive hemolytic anemia

methyldopa, penicillin

20

gray baby syndrome

chloramphenicol

21

hemolysis in G6PD deficiency

isoniazid, sulfonamides, depsone, primaquine, aspirin, ibuprofen,, nitrofurantoin

22

megaloblastic anemia

phenytoin, methotrexate, sulfa drugs

23

thrombocytopenia

heparin

24

thrombotic complications

OCPs, hormone replacement therapy

25

fat redistribution

protease inhibitors, glucocorticoids

26

gingival hyperplasia

phenytoin, Ca channel blockers, cyclosporine

27

hyperuricemia (gout)

pyrazinamide, thiazides, furosemide, niacin, cyclosporine

28

myopathy

fibrates, niacin, colchicine, hydroxycholoroquine, interferon-alpha, penicillamine, statins, glucocorticoids

29

osteoporosis

corticosteroids, heparin

30

photosensitivity

sulfonamides, amiodarone, tetracyclines, 5-FU