pharmacology: CNS drug list Flashcards Preview

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Flashcards in pharmacology: CNS drug list Deck (29):
1

what are the sedative-hypnotics?

barbiturates, benzos, alcohol

2

what are the barbiturates? mechanism?

phenobarbital and thiopental
mechanism: prolong GABA activity by increasing duration of Cl- channel opening with GABA mimetic acitivity - binding site on GABA A complex

3

what are the benzos? mechanism?

alprazolam, diazepam, lorazepam, midazolam, temazepam, oxazepam
mechanism: potentiate GABA by increasing the frequency of Cl- channel opening (GABA A)

4

benzo antagonist

flumazenil

5

busipirone mechanism and use

5 HT1A partial agonist
used for generalized anxiety disorders

6

what are the anticonvulsants

carbamazepine, ethosuximide, valproic acid, phenytoin, diazepam, lorazepam, gabapentin

7

what drug is used in seizure states and neuropathic pain

gabapentin

8

what are the anesthetics (IV)

fentanyl, ketamine, midazolam, propofol, thipental

9

what are teh neuromuscular blocking agents

depolarizing: succinylcholine
nondepolarizing: atracurium, mivacurium, tubocurarine

10

what are the inhaled anesthetics?

halothane, nitrous oxide

11

what are the local anesthetics

lidocaine, bupivacaine, mepivacaine, procaine, cocaine

12

what are the opioid full agonists?

morphine, meperidine, methadone, fentanyl, heroine

13

what are the opioid partial agonists?

buprenorphine, codeine

14

what are the opioid mixed agonist=antagonists

nalbuphine

15

what are the opioid antagonists?

naloxone, naltrexone, methylnaltrexone

16

what are the typical antipsychotics?

chlorpromazine, fluphenazine, thioridazine, haloperidol

17

what are the atypical antipsychotics?

clozapine, risperidone, olanzapine, aripiprazole, quetiapine, ziprasidone

18

what are the antiparkinsonian drugs?

DA agonists, MAO-B inhibitor, AAAD inhibitor, M blockers, COMT inhibitor, DA release and M blocker

19

what are the DA agonists?

levodopa, bromocriptine, pramipexole

20

what is the MAO-B inhibitor?

selegiline

21

what is the AAAD inhibitor?

carbidopa

22

what is are the M blockers?

benztropine, trihexiphenidyl

23

what is the COMT inhibitor?

tolcapone

24

what is the DA releaser and M blocker

amantadine

25

what are the antidepressants

MAOIs, TCAs, SSRIs

26

what are the MAOIs

phenelzine, tranylcypromine

27

what are the TCAs

amitriptyline, imipramine, clomipramine

28

what are the SSRIs

fluoxetine, paroxetine, sertraline

29

what is used for ADHD?

methylphenydate and atomoxetine