Flashcards in pharmacology: CNS drug list Deck (29):
what are the sedative-hypnotics?
barbiturates, benzos, alcohol
what are the barbiturates? mechanism?
phenobarbital and thiopental
mechanism: prolong GABA activity by increasing duration of Cl- channel opening with GABA mimetic acitivity - binding site on GABA A complex
what are the benzos? mechanism?
alprazolam, diazepam, lorazepam, midazolam, temazepam, oxazepam
mechanism: potentiate GABA by increasing the frequency of Cl- channel opening (GABA A)
busipirone mechanism and use
5 HT1A partial agonist
used for generalized anxiety disorders
what are the anticonvulsants
carbamazepine, ethosuximide, valproic acid, phenytoin, diazepam, lorazepam, gabapentin
what drug is used in seizure states and neuropathic pain
what are the anesthetics (IV)
fentanyl, ketamine, midazolam, propofol, thipental
what are teh neuromuscular blocking agents
nondepolarizing: atracurium, mivacurium, tubocurarine
what are the inhaled anesthetics?
halothane, nitrous oxide
what are the local anesthetics
lidocaine, bupivacaine, mepivacaine, procaine, cocaine
what are the opioid full agonists?
morphine, meperidine, methadone, fentanyl, heroine
what are the opioid partial agonists?
what are the opioid mixed agonist=antagonists
what are the opioid antagonists?
naloxone, naltrexone, methylnaltrexone
what are the typical antipsychotics?
chlorpromazine, fluphenazine, thioridazine, haloperidol
what are the atypical antipsychotics?
clozapine, risperidone, olanzapine, aripiprazole, quetiapine, ziprasidone
what are the antiparkinsonian drugs?
DA agonists, MAO-B inhibitor, AAAD inhibitor, M blockers, COMT inhibitor, DA release and M blocker
what are the DA agonists?
levodopa, bromocriptine, pramipexole
what is the MAO-B inhibitor?
what is the AAAD inhibitor?
what is are the M blockers?
what is the COMT inhibitor?
what is the DA releaser and M blocker
what are the antidepressants
MAOIs, TCAs, SSRIs
what are the MAOIs
what are the TCAs
amitriptyline, imipramine, clomipramine
what are the SSRIs
fluoxetine, paroxetine, sertraline