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Flashcards in Pharmocology Deck (21):
1

DMARDs

Disease-modifying Antirheumatic Agents

Used for rheumatic disease - early in he progression of the disease. Inhibit the immune response.
Ex: Rheumatrex (methotrexate), arava (lefunomide), antimalarial, plaquenl (hydroxychloroquine), gold componds, tumor necrosis factor inhibitors

High incidence of toxicity

2

Glucocorticoid

Corticosteroids: hormonal, anti-inflammatory, and metabolic effects to suppress articular and systemic disease.

Dermacot (hydrocorsone or cortisol), cordrol (prednisone), medrol methylprednisolone), decadrol (dexamethasone), nasonex (mometasone)

3

Major Side effects of Corticosteroids

immune suppression, mm atrophy, GI distress, glaucoma, adrenocortical suppression, Cushing syndrome, weakening with breakdown of supporting tissues, osteoporosis, tendon rupture/laxity/weakness, HTN,

Signs of toxicity: moon face, buffalo hump, and personality hanges

4

Nonopiod agents

analgesia, pain relief, some produce anti-inflammatory effects, some initiate anti-pyretic (fever reducing) properties

5

Acetaminophen

Tylenol - nonopioid agent, no inflammation properties - reduces fever (anti-pyretic)

6

Acetylsalicylic acid

Aspirin - non opiod agent, anti-inflammatory and reduction of risk of myocardial infarction
Potential of Reye syndrome in children

7

Naproxen

Aleve - anti-inflammatory non opiod agent

8

Celeoxib

Celebrex - anti-inflammatory non opiod agent

9

Opiod agents

Narcotics - for acute severe pain - stimulates receptors in CNS - dependency and withdrawal symptoms

Side effets: sedation, orthostatic hypotension, constipation, dependence and tolerance, respiratory depression,

Treatment should be scheduled 2 hours after administration

Examples: morphine, demerol (meperidine), oxycontin (oxycodone), sublimaze (fentanyl), Paveral (codeine)

10

Antiepileptic agents (types and side effects)

Types: barbiturates, benzodiazepines, carboxylic acids, hydantoins, iminostilbenes, succinimides, and second generation drugs

Side effects: ataxia, skin issues, behavioral hanges, GI, HA, vision changes, weight gain

Dilantin (phenytoin), Neurontin (gabapentin), seconal (secobarviatl), klonopin (clonazepam), depakote (valproic acicd),

11

Antispasticity agents

Side effects: drowsiness, confusion, HA, dizziness, generalized muscle weakness, heaptotoxicity (Dantrium), tolerance, dependence

Types: lioresal (baclofen), valium (diazepam), dantrium (dantrolene), zanaflex (tizanidine)

12

Dopamine Relacement Agents

For parkinson's disease. Able to cross the blood brain barrier

Side effects, arrhythmias (levadopa), GI distress, orthostatic hypotension, dyskinesias, mood/behavioral changes

Examlples: Sinemet or madopar (levadopa), symmetrel (amanadine)

13

Muscle relaxant agents

for mm spasms due to musculoskeletal or peripheral nerve injuries

Examples: valium (diazepam), flexerile cyclobenzaprine), paraflex (chlorzoxazone)

14

Ionto - Copper Sulfate

Positive. For fungal infections

15

Ionto - Lidocaine

Positive. For pain and inflammation

16

Ionto - Magnesium Sulfate

Positive. For mm spasms

17

Ionto - Zinc Oxide

Positive For healing, dermal ulcers and wounds

18

Ionto - Acetic Acid

Negative. For Calcium deposits and myositis ossificans

19

Ionto - Calcim Cloride

Negative. For scars, keloid, and mm spasms

20

Ionto - Iodine

Negative. For scars and adhesive capsulitis

21

Ionto - Salicycates

Negative. For mm and jt pain, and plantar warts